Significance of Zone of inhibition
Zone of inhibition, a key term in microbiology, describes the area surrounding an antimicrobial agent on an agar plate where microbial growth is suppressed. This clear area, often measured in millimeters, indicates the effectiveness of the agent. It's a crucial tool for assessing the antibacterial or antifungal properties of various substances, from plant extracts to antibiotics, and is used to determine the susceptibility or resistance of microorganisms. The size of the zone directly correlates with the agent's ability to inhibit microbial growth.
Synonyms: Inhibition zone, Antimicrobial susceptibility, Antibiotic resistance test, Inhibitory zone
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Zone of inhibition'
In Hinduism, the "Zone of Inhibition" metaphorically represents the area of protection or influence created by a substance or practice, such as a plant extract or medication. It signifies a boundary where negative influences, like harmful bacteria, are prevented from flourishing, reflecting the effectiveness of a remedy or approach.
From: International Research Journal of Ayurveda and Yoga
(1) This is the area around a substance where bacterial growth is inhibited, used to assess antibacterial activity.[1] (2) It was measured in mm for each organism with different extracts to evaluate anti-microbial activity.[2]
From: Journal of Ayurvedic and Herbal Medicine
(1) The text mentions the zone of inhibition, which is the area around a substance where bacterial growth is inhibited, indicating the effectiveness of the substance.[3] (2) This is a clear circular area that appears around a well in an agar plate, indicating the absence of bacteria and the effectiveness of a particular drug.[4] (3) This is the area around a substance, such as a plant extract, where the growth of bacteria is inhibited, and it is measured to determine the antimicrobial activity of the extract.[5] (4) This is the area around a substance where bacterial growth is inhibited, measured in millimeters, and it was used to determine the antibacterial property of Aloe vera extracts against Enterococcus faecalis.[6] (5) This is the area around the disc where the growth of microorganisms is prevented, which is measured to determine the effectiveness of the plant extracts in the disc diffusion method.[7]
From: Journal of Ayurveda and Integrated Medical Sciences
(1) This is a measure used in the invitro study to assess the antifungal activity of Somaraji Taila, it is the area where fungal growth is prevented.[8] (2) This is a measurement used to determine the antimicrobial activity of Vanga Bhasma, indicating the area where microbial growth is inhibited.[9] (3) This is a measurement used to determine the effectiveness of an antimicrobial agent, indicating the area around a drug-containing cavity where the growth of microorganisms is prevented.[10] (4) This term is used to describe the area around the wells where the antimicrobial activity is observed on agar plates, indicating the effectiveness of the tested compound against the microorganisms present.[11] (5) This term describes the area around a sample on a petri dish where the growth of a microbe is inhibited, which is used to measure the antidandruff activity.[12]
The concept of Zone of inhibition in scientific sources
The zone of inhibition is the area surrounding an antimicrobial agent where microbial growth is prevented. This measurement, often in millimeters, indicates the effectiveness of the agent by showing the area where bacteria or fungi are inhibited. It's used to assess the efficacy of antibacterial or antifungal substances.
From: International Journal of Pharmacology
(1) Positive results were established by the presence of clear zones around active extracts.[13] (2) Table 1 shows the diameter of this of bacterial organisms of N. nucifera pollen essential oil against various bacteria. Data are mean±SD.[14] (3) The produced by the crude ethanol extract was found to be 8-22 mm and n-hexane, chloroform, ethyl-acetate extracts were found to be 7-20 mm at a concentration of 500 μg disc –1.[15]
From: Asian Journal of Pharmaceutics
(1) The clear area around an antimicrobial substance on a bacterial culture plate, indicating the substance's ability to inhibit bacterial growth.[16] (2) This was observed after the incubation period in the disk diffusion method, indicating antibiotic effectiveness.[17] (3) The clear area around a well on an agar plate where bacterial growth is inhibited, indicating antibacterial activity.[18]
From: Onderstepoort Journal of Veterinary Research
(1) The area around an antibiotic disc where bacterial growth is inhibited, used to assess the susceptibility of bacteria to antibiotics, which helps choose a treatment.[19]
From: Journal of Medicinal Plants for Economic Development
(1) This is the area around a disc where bacterial or fungal growth is inhibited, indicating the effectiveness of the extract.[20] (2) The zone of inhibition is mentioned as the area around a disc where bacterial growth is inhibited, used in the antibacterial screening test.[21] (3) This is the area around the extract where the growth of microorganisms is inhibited.[22]
From: Journal of Public Health in Africa
(1) This is the area around an antibiotic disc where bacterial growth is inhibited, and its size indicates the susceptibility of the bacteria.[23]
From: International Journal of Pharmacology
(1) Zone of inhibition is the clear area around an antimicrobial agent on an agar plate where bacterial growth has been inhibited, indicating the agent's effectiveness.[24] (2) This is the clear area surrounding an antimicrobial agent on an agar plate where bacterial growth is prevented.[25] (3) The measurement of this area around an antibiotic disc indicates the susceptibility or resistance of the bacteria to that antibiotic.[26]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) The zone of inhibition was a key measurement obtained from the paper disc diffusion method, used to quantitatively assess the extent of antibacterial activity displayed by a flavonoid sample against the cultured H. pylori strains after incubation.[27] (2) The six clay samples within the bored holes do not inhibit the bacterial strains and hence they have no this, indicating they do not have any potent activities.[28] (3) Zone of inhibition was noted after 24 h incubation, and the result was compared with that of the European Committee on Antimicrobial Susceptibility Testing (EUCAST) database.[29]
From: Sustainability Journal (MDPI)
(1) The results obtained against both Gram-negative and Gram-positive bacterial strains and pathogenic fungi are graphically represented as a zone of inhibition (diameter) in Figure 6 and tabulated in Tables 1 and 2.[30] (2) The zone of inhibition, measured in millimeters, is used to quantify the antimicrobial activity of different extraction methods against various bacteria.[31] (3) It is a measure of a clear region with no microbial growth around a paper disc, representing the resistance or effective inhibition of microbial growth by an antimicrobial agent.[32]