Significance of Zone of inhibition
The Zone of Inhibition is a key measurement in microbiology that refers to the clear area surrounding an antimicrobial agent on a culture plate where bacterial growth is prevented. This area is used to assess the effectiveness of various antimicrobial substances, such as antibiotics or plant extracts, against specific pathogens. The size of the zone, measured in millimeters, indicates the level of antimicrobial activity and helps researchers evaluate the efficacy of treatments against different bacterial strains.
Synonyms: Inhibition zone, Antimicrobial susceptibility, Antibiotic resistance test, Inhibitory zone
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The concept of Zone of inhibition in scientific sources
The Zone of Inhibition is a clear area around an antimicrobial disc, indicating the effectiveness of the substance in preventing bacterial or fungal growth. It is measured during testing to evaluate microbial susceptibility.
From: The Malaysian Journal of Medical Sciences
(1) Zone of inhibition is a measurement used in the disc diffusion method and agar well diffusion method to assess the antibacterial activity of substances like honey.[1] (2) This is the area around an antibiotic disc where bacterial growth is inhibited, and its size indicates the susceptibility of the bacteria to the antibiotic.[2] (3) An area surrounding an antibiotic disc where microbial growth is prevented, used as a measure of bacterial susceptibility.[3]