Significance of Vascular endothelial growth factor
Vascular endothelial growth factor (VEGF) is a crucial protein that promotes the formation of new blood vessels, significantly impacting processes like angiogenesis, tumor growth, and wound healing. This growth factor plays a vital role in normal physiological functions and is implicated in various pathological conditions, including cancer and diabetic retinopathy. Elevated levels of VEGF are often associated with tumor progression, making it a focus for targeted therapies aimed at inhibiting angiogenesis and addressing diseases related to abnormal blood vessel formation.
Synonyms: Vegf, Vascular permeability factor
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The concept of Vascular endothelial growth factor in scientific sources
Vascular endothelial growth factor (VEGF) is a crucial protein that stimulates blood vessel growth, essential in healing and revascularization, particularly noted for its involvement in diabetic retinopathy pathology.
From: The Malaysian Journal of Medical Sciences
(1) This is a growth factor secreted by mast cells that can promote tumour proliferation by stimulating fibroblast growth and angiogenesis, as discussed in the text.[1] (2) This is a protein that promotes the formation of new blood vessels, and SEMA3B was shown to downregulate its signaling.[2] (3) This is a growth factor that promotes the growth of blood vessels, and it is being investigated in the context of lupus nephritis.[3] (4) A signal protein that stimulates the formation of blood vessels, inhibited by certain plant extracts like Toona sinensis in endothelial cells.[4] (5) A signaling protein that stimulates the formation of blood vessels, explored in the context of its expression and correlation with prognosis in synovial sarcoma.[5]