Significance of Toxicity profile
Toxicity profile refers to the comprehensive characterization of harmful effects associated with substances, particularly during drug testing and evaluation. This involves identifying and quantifying impurities, assessing long-term safety concerns, and analyzing potential adverse effects across various dosages. Key aspects include evaluating safety levels, mutagenicity, and organ toxicity, as well as conducting experimental studies on animals. The text highlights the necessity of understanding the toxicity profile for various drugs, including those like Kaseesa Drava and Vasaguduchyadi Kwatha.
Synonyms: Toxicity assessment, Safety profile, Risk assessment
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The concept of Toxicity profile in scientific sources
The Toxicity profile analyzes the harmful effects of substances, essential for assessing safety. It highlights the need for a detailed understanding of potential adverse effects, particularly for Unmada Gaja Kesari Rasa and the lacking data for Vasaguduchyadi Kwatha.
From: World Journal of Pharmaceutical Research
(1) A detailed description of the potential harmful effects and risks associated with a drug, including symptoms of overdose and adverse reactions.[1] (2) The potential of a substance to cause harm, which is assessed by examining biomarkers in blood to ascertain kidney and liver health.[2] (3) An assessment of the potential harmful effects of a drug, including levels of organ toxicity and other adverse effects.[3] (4) The characterization of adverse effects and safety concerns associated with the long-term use of Karisalai Karpam.[4] (5) The evaluations related to the harmful effects that impurities in a drug may have, necessitating their identification and quantification in Kaseesa Drava.[5]
From: AYU (Journal of Research in Ayurveda)
(1) A comprehensive assessment of the adverse effects associated with a particular substance or extract when administered at various dosages.[6] (2) A comprehensive understanding of the safety and potential harmful effects of a drug or formulation, which is lacking for Vasaguduchyadi Kwatha as noted in the text.[7]
From: Journal of Ayurveda and Holistic Medicine
(1) An analysis of the potential toxic effects of a substance, crucial in assessing the safety of Unmada Gaja Kesari Rasa.[8]
From: International Ayurvedic Medical Journal
(1) An assessment of the harmful effects and safe dosage levels of a certain substance or compound.[9]