Significance of Toxic epidermal necrolysis

Toxic epidermal necrolysis (TEN) is a life-threatening skin condition characterized by widespread detachment of the epidermis and mucous membranes, often triggered by adverse drug reactions. It is similar to Stevens-Johnson syndrome but presents as a more severe form, affecting over 30% of the body surface area and associated with a high mortality rate of 20-25%. This severe condition leads to significant morbidity due to rapid skin shedding, necrosis, and potential ocular complications.

Synonyms: Stevens-johnson syndrome, Ten, Severe cutaneous adverse reaction, Lyell's syndrome, Epidermal necrolysis

The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.

Hindu concept of 'Toxic epidermal necrolysis'

Hinduism Books

In Hinduism, Toxic epidermal necrolysis may be viewed as a significant medical condition, akin to Stevens-Johnson Syndrome, emphasizing the importance of understanding its management within the broader context of health and wellness.

Significance in Ayurveda (science of life):
Ayurveda Books

(1) This is another medical condition that is discussed in the context of its management, similar to the Stevens-Johnson Syndrome mentioned previously.[1]

Ayurveda is a branch of Indian science dealing with medicine, herbalism, taxology, anatomy, surgery, alchemy and related topics. Traditional practice of Ayurveda in ancient India dates back to at least the first millenium BC. Literature is commonly written in Sanskrit using various poetic metres.

The concept of Toxic epidermal necrolysis in scientific sources

Science Books

Toxic epidermal necrolysis is the most severe form of Stevens-Johnson syndrome, a life-threatening skin condition marked by extensive epidermal detachment and significant morbidity, often induced by medications like phenytoin, resulting in widespread skin cell death.

Significance in Scientific journals, articles, etc.:

(1) This is a condition that is highly associated with the HLA-B*1502 allele.[2] (2) A life-threatening condition resembling Stevens Johnson syndrome, characterized by widespread skin and mucosal erosion.[3]

This section includes scientific research in the field of healthcare, often involving traditional medicine systems such as Ayurveda, Unani, Siddha and Holistic health. It includes papers from scientific journals classified as either original, clinical or experimental research, review articles or case reports.