Significance of Topical administration
Topical administration, across various perspectives, consistently refers to the direct application of a substance, typically a drug or treatment, onto the skin or mucous membranes. This method aims for localized effects, such as in wound care, hair loss treatment, or eye conditions, often to minimize systemic absorption and side effects. The application can involve diverse formulations like creams, gels, or drops, and is preferred in various medical scenarios for its targeted delivery and effectiveness.
Synonyms: Topical application, Local administration, Dermal application, Surface application
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Topical administration'
In Hinduism, topical administration involves directly applying treatments, particularly Ayurvedic preparations, to the skin. This method utilizes the skin as a primary route for drug delivery, offering a direct and localized approach to treatment.
From: International Research Journal of Ayurveda and Yoga
(1) This of extracts derived from plant medicines, animal tissues, mineral drugs, and lipids is done by heating their admixture in a closed chamber.[1] (2) This is the administration method for Brihatsindoordya Taila and Brihatsindoordya Taila Malahar in the study.[2] (3) This is the method of applying drugs directly to the skin, which is the main route for delivering drugs through a topical drug delivery system.[3]
From: Journal of Ayurvedic and Herbal Medicine
(1) This refers to the method of applying a treatment directly to the skin, and the text mentions various Ayurvedic preparations used in this way.[4]
The concept of Topical administration in scientific sources
Topical administration involves directly applying drugs to skin or mucous membranes for localized effects. This method minimizes systemic absorption and is used for various conditions, including skin, nasal, and eye treatments, often employing creams, gels, or drops.
From: Asian Journal of Pharmaceutics
(1) After the topical administration of the developed in situ gel formulations and timolol eye drop, the levels of drugs in the aqueous humor of rabbits were measured.[5] (2) PEGs have shown few serious adverse effects like hyperosmolarity, metabolic acidosis and renal failure upon topical administration in burn patients.[6] (3) Hydrogel-thickened microemulsion was used for this of a drug molecule at an extremely low concentration.[7] (4) This is the application of a drug to the surface of the body. The topical administration of antimicrobial or wound healing agents in the form of solution or gel directly to the wound site will diffuse rapidly and gets eliminated from the site.[8] (5) This is the most favored route for managing ocular inflammation, as it delivers higher drug concentrations to the eye.[9]
From: International Journal of Pharmacology
(1) Effect of postoperative this of magnesium sulfate on pain relief in paediatric adenotonsillectomy: A randomised controlled study.[10] (2) When combined with oral therapy, it synergizes the bactericidal effect of cefadroxil in the skin region.[11] (3) Treatments were performed by this method of 2 g of the cream on a fixed area (4×4 cm 2) on the right superior region of the back.[12] (4) The examination of polysaccharides as potential antioxidative compounds for this using a lipid model system.[13] (5) This refers to the application of 10% sildenafil in patients with CAF, which significantly reduces anal sphincter pressure.[14]
From: Journal of Public Health in Africa
(1) This refers to applying collagen directly to the skin, and the study discusses its limitations, such as poor permeability due to the molecule's size, and potential strategies.[15]
From: Journal of Medicinal Plants for Economic Development
(1) This is a method of applying herbal medicine directly to the skin or affected area, as part of the treatment process.[16]
From: International Journal of Pharmacology
(1) Topical administration involves applying a substance directly to the surface of the body, such as the topical application of rambutan honey to oral mucosal wounds.[17]
From: Sustainability Journal (MDPI)
(1) "Topical administration" of mangiferin promotes wound healing, implying that applying mangiferin directly to the skin can aid in recovery.[18]