Significance of Theca cells
Theca cells, according to Ayurveda, are ovarian cells producing excess androgens due to elevated LH in PCOS. Science notes their involvement in follicular development, observing increased proliferation markers in zingerone-treated rats. Health Sciences highlights eNOS expression in these cells during follicular growth and in granulosa cells, indicating nitric oxide's role. Additionally, these cells contribute to hormone overproduction in PCOS, emphasizing their significance across different disciplines.
Synonyms: Thecal cells, Ovarian theca cells, Steroidogenic cells, Endocrine cells
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Theca cells'
In Hinduism, Theca cells are ovarian cells that, when affected by high LH levels in Polycystic Ovary Syndrome (PCOS), produce excessive androgens.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) Ovarian cells that, under the influence of elevated LH in PCOS, produce increased amounts of androgens.[1]
The concept of Theca cells in scientific sources
Theca cells, found in the ovary, express eNOS during follicular growth and hormone overproduction. They are involved in follicular development, with Ki67 expression increasing upon zingerone treatment.
From: The Malaysian Journal of Medical Sciences
(1) Cells in which eNOS is expressed during follicular growth and in the granulosa cells of the follicle wall, and after ovulation, eNOS is expressed in the yellow body, showing NO's role.[2]
From: Journal of Metabolic Health
(1) These are the specific cells within the ovary that are responsible for the overproduction of hormones, thus contributing to the syndrome's characteristics.[3]
From: Asian Journal of Pharmaceutics
(1) The infiltration of macrophages, immune cells known for their inflammationpropagating role, into key ovarian compartments, like this.[4]
From: International Journal of Pharmacology
(1) Theca cells in the ovary are involved in follicular development, and their expression of the proliferation marker Ki67 was observed to increase in zingerone-treated female rats.[5]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) Theca cells are ovarian cells that are stimulated by luteinizing hormone to increase androgen production, contributing to the hyperandrogenemia observed in polycystic ovary syndrome.[6]