Significance of Tandem mass spectrometry
Tandem mass spectrometry is an advanced analytical technique that uses two mass spectrometers in sequence to enhance the analysis of complex samples. This method allows for detailed analysis by separating ions based on their mass and charge, and it often involves multiple rounds of mass spectrometry with fragmentation for increased specificity and sensitivity in detecting analytes. It is particularly useful for qualitative and quantitative analysis in biological samples and is often coupled with other separation techniques, like chromatography.
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The concept of Tandem mass spectrometry in scientific sources
Tandem mass spectrometry is a sophisticated analytical technique that utilizes sequential mass spectrometers to filter and fragment ions, improving the analysis of complex samples through enhanced sensitivity and specificity in the results.
From: World Journal of Pharmaceutical Research
(1) A technique that allows for the analysis of complex mixtures by using two mass spectrometers in sequence, applicable in determining paroxetine.[1] (2) An analytical technique that combines mass spectrometry with a second stage of mass analysis to increase specificity and sensitivity in detecting analytes.[2] (3) An advanced technique that allows the analysis of complex mixtures by combining mass spectrometry with additional separation techniques.[3] (4) An analytical technique used for the qualitative and quantitative analysis of samples, often coupled with chromatography for bioanalysis.[4] (5) A mass spectrometry technique that enables detailed analysis by separating ions based on mass and charge in a two-stage process.[5]