Significance of Tablet hardness
Tablet hardness is a critical measure of a tablet's resistance to deformation or breakage under pressure. It ensures product durability and protects integrity during handling and transportation. Assessing tablet hardness involves measuring the force required to break the tablet, typically using a hardness tester, and is crucial for quality control in tablet formulation. This measurement impacts the tablet's stability, resistance to mechanical stress, and overall performance, making it essential for maintaining the effectiveness of active ingredients during storage and use.
Synonyms: Tablet strength, Tablet durability
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Tablet hardness'
In Hinduism, tablet hardness signifies the durability and stability of medicinal tablets, crucial for their effectiveness and bioavailability, as it reflects their ability to resist pressure and maintain integrity through various processes.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) This refers to the resistance of the tablet to breaking, and the hardness of the Kaidaryadi Ghanavati tablets was measured to assess their quality and potential impact on bioavailability.[1] (2) Tablet hardness is a measure of the force needed to crush or break a tablet, which is crucial for ensuring tablets remain intact during packaging, shipping, and handling.[2] (3) A quantitative parameter measured to determine the resistance of the N-Dopa tablets to breaking under pressure, expressed in kg/cm2.[3] (4) This is a measure of how well the tablet can withstand pressure, and it relates to the time it takes to disintegrate in the body.[4]
The concept of Tablet hardness in scientific sources
Tablet hardness is a crucial measure of a tablet's resistance to mechanical stress and deformation, influenced by binding efficiency, and its ability to endure handling shocks, ensuring structural integrity within specified strength ranges.
From: Asian Journal of Pharmaceutics
(1) A measure of the force required to break a tablet, indicating its resistance to chipping, abrasion, or breakage.[5] (2) It is an important factor affecting the disintegration of tablets and influences the disintegration time.[6] (3) The resistance of tablets to shipping or breakage depends on this physical property.[7] (4) This was tested using a Monsanto hardness tester, with the hardness of the tablets measured.[8] (5) This is a test that determines the mechanical integrity and resistance to breakage of the matrix tablets.[9]