Significance of T cell subsets
T cell subsets are specialized T cell populations with unique roles in immunity. These subsets, including Th1, Th2, and regulatory T cells, are investigated in various contexts. Research explores how these subsets respond to specific peptides, their roles in diseases like Leishmania infections, and their association with endothelial function and oxidative stress in people living with HIV. Studies also examine the impact of haemodialysis and viral infections, such as RSV, on these different types of T lymphocytes.
Synonyms: Cd4+ t cells, Cd8+ t cells, Th1 cells, Th2 cells, Memory t cells
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The concept of T cell subsets in scientific sources
T cell subsets are specialized T cell populations (e.g., Th1, Th2) with unique immune roles. They are identified using markers like CD31 and are studied in HIV, Leishmania, and other infections, as well as in conditions like schizophrenia, highlighting their importance in immune responses and disease.
(1) T-cell subsets can be identified using CD31, and CD31 is a marker of recent thymic emigrants among CD4 + T-cells, but not CD8 + T-cells or gamma delta T-cells.[1] (2) These are investigated in the context of human immunodeficiency virus infection, providing insights into the immune response.[2] (3) T-cell subsets and vascular compliance in PLWH were reported in recent studies, and the study assessed whether T-cell subsets were associated with markers of endothelial function and oxidative stress.[3] (4) These are the different types of T cells in the blood, and this study aimed to evaluate the immediate influence of haemodialysis on these cells in people living with HIV.[4]
(1) The text refers to the regulator and effector functions of T-cell subsets in human Leishmania infections, highlighting their role in the disease.[5] (2) These are different groups of T cells, each with distinct functions, and in this study, researchers aimed to determine which subsets respond to specific peptides.[6]
(1) These are distinct populations of T lymphocytes, a type of white blood cell crucial for the immune response, and their characteristics have been compared between different groups of individuals with schizophrenia.[7] (2) Different types of T lymphocytes, such as CD3+, CD4+, and CD8+, which are important components of the immune system and were affected by RSV infection.[8]