Significance of Systemic disease

Systemic disease refers to medical conditions that impact multiple systems or the entire body, rather than being restricted to a specific area. These diseases include conditions like systemic lupus erythematosus, diabetes mellitus, and cardiovascular diseases, which may present with oral health manifestations such as periodontal disease. In clinical studies, systemic diseases are often used as exclusion criteria to ensure participants are not affected by conditions that could compromise their health or influence study outcomes.

Synonyms: Systemic condition, Systemic disorder, Systemic illness, Widespread disease

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The concept of Systemic disease in scientific sources