Significance of Structure-activity relationship
Synonyms: Structure-activity analysis, Qsar, Pharmacophore analysis, Structure-property relationship, Chemical biology, Medicinal chemistry, Molecular modeling
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The concept of Structure-activity relationship in scientific sources
From: International Journal of Pharmacology
(1) Structure-activity relationships are explored for norsecofriedelanes to understand how their chemical structure relates to their spasmolytic activity.[1] (2) The connection between the chemical structure of compounds and their biological effects, important for understanding how to develop new drugs or supplements.[2] (3) The connection between a molecule's chemical structure and its biological activity.[3] (4) This field of study examines how the chemical structure of a molecule relates to its biological activity, helping to design more effective compounds.[4] (5) Structure-activity relationship studies investigate how changes in a molecule's structure affect its biological activity, applied to dihydropyridines.[5]
From: The Malaysian Journal of Medical Sciences
(1) This refers to the relationship between the chemical structure of a molecule and its biological activity, which is very important.[6]
From: International Journal of Pharmacology
(1) These studies investigate how the chemical structure of compounds like flavonolignans and flavones relates to their ability to inhibit bacterial resistance mechanisms.[7] (2) The study of how the chemical structure of a compound relates to its biological activity.[8] (3) This involves understanding how the chemical structure of a compound relates to its biological activity, crucial for drug development.[9] (4) The correlation examined between the chemical structure of compounds and their pharmacological activities, leading to assumptions about essential structural features.[10] (5) This analysis aimed to understand how the chemical structure of the synthesized compounds relates to their observed pharmacological activities, suggesting factors like peptide unit size and specific atoms influence potency.[11]