Significance of Slower drug release
Slower drug release, as observed in Health Sciences, is a beneficial property of certain drug formulations that aim to extend the period a drug is released into the body. LPHNPs loaded with nateglinide demonstrated slower release compared to PNPs at 24 hours. Increasing ethyl cellulose content reduces drug cluster formation, contributing to this slower release, particularly noticeable with higher amounts of nanoparticles in matrices. Release from nanostructures is a key factor in achieving this extended release profile.
Synonyms: Delayed drug release, Extended drug release, Sustained drug release, Controlled drug release, Extended release, Sustained release, Controlled release
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The concept of Slower drug release in scientific sources
Slower drug release extends drug release time, observed with increased nanoparticles. LPHNPs loaded with nateglinide exhibited slower release compared to PNPs at 24 hours, influenced by ethyl cellulose content.
From: Asian Journal of Pharmaceutics
(1) The LPHNPs loaded with nateglinide showed slower release as compared to PNPs at 24 h.[1] (2) Release from nanostructure is a beneficial property of the formulation.[2] (3) This was observed in the matrices with increasing the amount of NPs.[3] (4) Increasing ethyl cellulose content increases total number of ethyl cellulose particles that leads to reduced formation of drug clusters resulting in this.[4]