Significance of Silymarin
Silymarin, a compound derived from milk thistle, is widely recognized for its hepatoprotective properties. It's often used as a standard or positive control in studies, comparing its effects to various experimental treatments for liver damage. These studies highlight Silymarin's antioxidant and anti-inflammatory actions, showing its potential in managing hepatic disorders and mitigating damage from toxins. Silymarin's ability to protect against oxidative stress and promote liver health makes it a valuable reference in assessing new treatments.
Synonyms: Milk thistle extract, Silybum marianum, Flavonolignan complex, Herbal supplement, Milk thistle, Liver tonic, Antioxidant.
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Silymarin'
In Hinduism, Silymarin is understood as a compound extracted from milk thistle. It is a flavonoid complex, specifically from Silybum marianum. Known for its hepatoprotective and antioxidant qualities, it is the active element in liver protection.
From: International Research Journal of Ayurveda and Yoga
(1) Silymarin has multiple effects on the Hepatitis C virus lifecycle, according to research published in the Journal of Hepatology.[1] (2) This is a flavonoid complex found in Silybum marianum, which is the key bioactive component responsible for its hepatoprotective effects, offering antioxidant benefits.[2]
From: Journal of Ayurvedic and Herbal Medicine
(1) A compound derived from milk thistle, known for its hepatoprotective properties, used as a positive control in studies of Bauhinia purpurea's liver-protective effects.[3]
The concept of Silymarin in scientific sources
Silymarin is a hepatoprotective agent, often used as a standard reference drug in liver studies. It is derived from milk thistle and is known for its antihepatotoxic properties. It is used to compare the effectiveness of other substances in treating liver damage.
From: International Journal of Pharmacology
(1) Silymarin is a compound compared to oregano in terms of its ameliorative effect on experimentally induced hepatic encephalopathy, as referenced in the text.[4] (2) The rats treated with ethanolic extract of C. grandis and this substance, experienced a significant decrease in certain levels.[5] (3) It is a hepatoprotective flavonolignan extract of S. marianum seeds whose quality and quantity in fruits depends upon the growing conditions of plant.[6] (4) This is a known hepatoprotective agent, and studies compared the effects of dried leaves of chicory with it on liver enzyme levels.[7] (5) A substance used as a positive control in the study, pretreated to mice at 50 mg kg -1.[8]
From: Asian Journal of Pharmaceutics
(1) A substance with comparative pharmacokinetics to silipide in rats.[9] (2) This is a compound with high efficacy and prolonged action, with its formulation described in the text.[10] (3) Research indicates bioavailability and activity of phytosome complexes from botanical polyphenols, including silymarin, curcumin, green tea, and grape seed extracts.[11] (4) This is the main ingredient in milk thistle, which can be more efficiently transported to the liver using phytosomes.[12] (5) This substance is used in the preparation and evaluation of gastroretentive floating tablets.[13]
From: Journal of Medicinal Plants for Economic Development
(1) This substance serves as a positive control in the experiment, used to compare the efficacy of neem seed oil in its ability to protect the liver from damage.[14]
From: International Journal of Pharmacology
(1) A compound used as a positive control in studies investigating liver protection, known for its antioxidant and anti-inflammatory properties.[15] (2) A natural polyphenolic molecule with antioxidant characteristics that can react with free radicals and reactive oxygen species.[16] (3) A reference drug used in studies to evaluate hepatoprotective effects, often compared against experimental treatments.[17] (4) A standard drug used as a control in studies investigating liver protection, known for its ability to prevent elevated serum enzymes and lipid peroxidation.[18] (5) A standard drug used as a reference in the study, administered to compare its hepatoprotective effect with that of radish juice.[19]