Significance of Sham operation
Sham operation, as defined in scientific research, is a control procedure conducted on a group of animals where no actual nerve ligation occurs. This method is essential for ensuring the validity of comparative studies by providing a baseline to compare against the effects of the actual procedure. By utilizing sham operations, researchers can assess the specific impacts of surgical interventions without the confounding variables introduced by real surgical alterations.
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The concept of Sham operation in scientific sources
The keyphrase "Sham operation" refers to a control method in research involving animals, where no actual nerve ligation occurs. This procedure helps validate comparative studies by providing a baseline for comparison without treatment effects.
From: The Malaysian Journal of Medical Sciences
(1) This is the control group in the experiment, where mice underwent a procedure without the 5/6 SN procedure.[1]