Significance of Sepsis
Sepsis, a critical medical concern, is defined as a life-threatening condition stemming from the body's overwhelming response to infection. It's characterized by widespread inflammation, potentially leading to organ damage, failure, and even death. The condition can arise from various infections, including those caused by bacteria, and is often associated with systemic inflammatory response syndrome (SIRS). Sepsis can complicate wound healing and is a significant cause of mortality.
Synonyms: Septicemia, Blood poisoning, Systemic infection, Severe infection, Infection, Septic shock
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Sepsis in scientific sources
Sepsis is a life-threatening condition stemming from the body's overwhelming response to infection, often leading to systemic inflammation and organ dysfunction. It is characterized by a dysregulated immune response and can result from various infections, requiring careful management and treatment.
From: International Journal of Pharmacology
(1) A condition implicated by some bacteria tested in the study, referring to a life-threatening response to infection.[1] (2) Sepsis is identified as a significant global health concern, characterized by a systemic response stemming from acute infections, particularly those caused by Gram-positive or Gram-negative bacteria, leading to physiological, pathological, and biochemical abnormalities.[2] (3) Sepsis is a life-threatening condition characterized by a dysregulated immune response, and research examines the interplay of cytokines and nitric oxide in its pathogenesis.[3] (4) This systemic inflammatory response was considered an adverse event in the study, and its incidence was comparable between patients who received tranexamic acid and those who received normal saline.[4] (5) A life-threatening condition caused by the body's response to infection, where Pentoxifylline has been investigated for its potential to reduce mortality and morbidity.[5]
From: The Malaysian Journal of Medical Sciences
(1) A potentially fatal complication that can result from bowel perforation.[6] (2) This term describes a life-threatening condition caused by the body's response to an infection, and it is one of the indications for taking a sample of cerebrospinal fluid.[7] (3) This is a life-threatening condition that resulted in the death of one of the patients in the study, caused by a severe infection.[8] (4) This is a life-threatening condition caused by the body's response to an infection, and diverting the first few milliliters of blood into a pouch can reduce the risk of sepsis from skin bacteria.[9] (5) A life-threatening condition caused by the body's overwhelming response to an infection is referred to as sepsis, which can increase the length of a patient's hospital stay.[10]
From: South African Family Practice
(1) Delirium is an important indicator of this in the older patient and formed the basis of daily vitals.[11] (2) The presence of two or more of the following: Temperature ≥38 °C or ≤36 °C, Heart rate ≥90 bpm, Respiratory rate ≥20 breaths per min or PaCO 2 ≤32 mmHg, White cell count >12 000/mm 3 or <4 000/mm 3 or >10% immature bands, Anion gap acidosis.[12]
From: Journal of Public Health in Africa
(1) A life-threatening condition, and its treatment is included in basic emergency obstetric care.[13]
From: South African Journal of Physiotherapy
(1) Sepsis is a life-threatening condition that can result from infection and the patient’s immune system being in disarray and the patient becomes very susceptible to infection which might result in septic syndrome and ultimately multiple organ dysfunction.[14]
From: International Journal of Pharmacology
(1) Sepsis is a life-threatening condition associated with elevated levels of human resistin, indicating its involvement in severe inflammatory responses.[15] (2) If MRSA infections go untreated, they can become debilitating and lead to sepsis, which is an exaggerated bodily response to inflammation.[16] (3) A life-threatening systemic inflammatory response to infection, potentially leading to organ damage.[17] (4) A systemic inflammatory disease that is a primary cause of renal injury and can lead to multiple organ damage.[18] (5) A life-threatening condition arising from the body's response to infection, diagnosed in peritonitis cases through physical signs and biochemical measurements.[19]