Significance of Safety margin
Safety margin refers to the range within which a medicinal substance can be safely used without causing adverse effects. It includes the difference between effective and harmful doses, specifically noting how much of Semecarpus anacardium and other substances like W. lateritia extracts can be administered without leading to toxicity. A higher safety margin indicates a safer drug, ensuring that herbal medicines can be used effectively while minimizing the risk of adverse effects.
Synonyms: Cushion, Safeguard, Protection, Buffer zone, Margin of safety
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Safety margin in scientific sources
Safety margin is the measure indicating the safe dosage of Semecarpus anacardium that can be consumed without adverse effects, highlighting the threshold before potential harm occurs.
From: World Journal of Pharmaceutical Research
(1) The range within which a treatment can be administered without causing significant harm.[1] (2) The calculated difference between effective and harmful doses of a substance, applied to establish the safety of W. lateritia extracts in the study.[2] (3) The range within which a medicinal substance can be safely used without causing adverse effects.[3] (4) The concentration of a drug at which toxic effects begin to appear; a higher margin indicates a safer drug.[4]
From: AYU (Journal of Research in Ayurveda)
(1) The buffer levels established to ensure the safe use of herbal medicines without adverse effects.[5]
From: International Ayurvedic Medical Journal
(1) The measure of how much Semecarpus anacardium can be safely administered before it causes harmful effects.[6]