Significance of Renin-angiotensin system
The renin-angiotensin system (RAS) is a crucial hormonal system, primarily regulating blood pressure and fluid balance. It's frequently targeted in treating hypertension and related conditions, with medications like ACE inhibitors and ARBs. The RAS can be activated in various scenarios, including diabetic nephropathy and during COVID-19 infection. Its influence extends to cardiovascular diseases, kidney functionality, and inflammation. The system is also linked to muscle function and sarcopenia, emphasizing its broad impact on overall health.
Synonyms: Renin-angiotensin-aldosterone system, Angiotensin system
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Renin-angiotensin system'
In Hinduism, the Renin-angiotensin system, a hormonal system, manages blood pressure. Exercise positively influences it, while low sodium or sympathetic stimulation activates it. It regulates blood pressure via vasoconstriction and sodium retention, potentially causing hypertension.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) The renin angiotensin system is a hormonal system that affects the control of blood pressure and is activated in response to reduced sodium levels in the blood or stimulation from the sympathetic nervous system.[1] (2) This is a hormonal system that helps regulate blood pressure, and exercise has a favorable effect on it, as described in the context of the text.[2]
From: International Research Journal of Ayurveda and Yoga
(1) Ischemia of the kidneys causes elevation of blood pressure by activation of the renin-angiotensin system.[3] (2) This is a hormonal system that regulates blood pressure through vasoconstriction and sodium retention, which can lead to hypertension.[4]
The concept of Renin-angiotensin system in scientific sources
The renin-angiotensin system (RAS) is a vital hormonal system regulating blood pressure and fluid balance. It's implicated in various health conditions, including hypertension, kidney disease, and cardiovascular issues. The RAS is a therapeutic target for many conditions, and is often influenced by medications, dietary factors, and other physiological processes.
From: South African Family Practice
(1) A hormonal system that regulates blood pressure and fluid balance, the blocking of which with specific drugs is a key component in managing hypertension in diabetics.[5] (2) Suppression of the renin angiotensin system (RAS) in diabetic patients with microalbuminuria seems to convey specific benefit in terms of renal and cardiovascular protection, as stated in the document.[6] (3) This biological system is a crucial focus in treating a specific medical condition, with various inhibitors being studied to understand their impact.[7] (4) In people below 55 years of age, treatment should be initiated with a RAS blocker, such as an ACE inhibitor or an ARB, highlighting the importance of this system in blood pressure management.[8] (5) This is activated in patients with hypotension, and may experience dizziness, fatiguability, weakness, syncope, and/ or low blood pressure.[9]
From: International Journal of Pharmacology
(1) The renin-angiotensin system is activated by visfatin, contributing to detrimental effects in diabetic nephropathy and promoting fibrosis.[10] (2) The renin-angiotensin system is a biological pathway where Angiotensin II is the sole active peptide, regulating vascular injury through its actions on endothelial function.[11] (3) This system is updated in the context of its relationship with diabetes and its impact on vascular health.[12] (4) A system influencing cardiovascular morbidities, particularly in ischemia reperfusion damage, and affected by ramipril.[13] (5) A hormonal system that is activated in diabetic nephropathy, contributing to the thickening of the glomerular basement membrane and expansion of mesangial cells.[14]
From: The Malaysian Journal of Medical Sciences
(1) This is a system in the body that can contribute to inflammation and fibrosis in the context of inflammatory bowel disease, offering a therapeutic target.[15] (2) This is a system that interacts with inflammation, interleukin-6, and dietary sodium in relation to hypertension, as stated in the text.[16] (3) This is abbreviated as RAS, and it is a term that is used within the provided text, and it is used in relation to the cardiovascular disease.[17] (4) The renin-angiotensin system is a hormonal system involved in blood pressure regulation and is linked to muscle function and the development of sarcopenia.[18] (5) A hormone system that regulates blood pressure and fluid balance, and interacts with dyslipidemia impacting therapy for hypertension and coronary artery disease.[19]
From: South African Journal of HIV Medicine
(1) This is a major regulator of blood pressure and vascular response to injury, and it is often targeted with medications to treat hypertension and related conditions.[20]
From: International Journal of Pharmacology
(1) The Renin-Angiotensin System (RAS) plays a role in blood pressure regulation, and its concentration can be affected by chronotherapy with valsartan.[21] (2) The renin-angiotensin system is an example of a neurohumoral system that may become activated during myocardial remodelling, contributing to cardiovascular changes.[22] (3) The renin angiotensin system is implicated in Doxorubicin-mediated physiological toxicities, particularly cardiotoxicity, with Angiotensin II being a major pathophysiological factor.[23] (4) A system that plays a vital role in maintaining cardiovascular homeostasis, particularly observed in studies related to acute liver failure.[24]