Significance of Renal impairment
Renal impairment, as discussed across various fields, refers to a condition where the kidneys do not function properly. In Ayurveda, it can impact gout management, while in Science, it is studied in relation to drug treatments. Psychiatry highlights the need for caution and dosage adjustments. Health Sciences describes it as a decrease in kidney function, which can be caused by medications, complications, or underlying conditions, and affects drug metabolism and excretion, often requiring dose adjustments. It is often identified by measuring the glomerular filtration rate.
Synonyms: Kidney dysfunction, Renal failure, Kidney impairment, Renal insufficiency, Reduced kidney function, Nephropathy, Kidney injury, Kidney disease, Renal damage
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Renal impairment'
In Hinduism, renal impairment involves using Gokshuradi Guggulu to manage fluid overload and strengthen the kidneys and heart. The condition, where kidneys fail, causes systemic issues like hyperacidity and anemia. It also impacts gout management, potentially limiting treatment.
From: International Research Journal of Ayurveda and Yoga
(1) A condition for which patients were excluded from the study on Ashmarihar Kasaya.[1]
From: Journal of Ayurvedic and Herbal Medicine
(1) Chronic diseases of this nature can cause hyperacidity, anemia, hypocalcemia, and hypoprotienaemia, indicating the systemic impact of such conditions.[2]
From: Journal of Ayurveda and Integrated Medical Sciences
(1) This is a condition where the kidneys do not function properly, which can affect how gout is managed, potentially limiting medication options and increasing the risk of adverse effects.[3] (2) Gokshuradi Guggulu, known for its diuretic action, not only reduces fluid overload in this condition but also strengthens the renal and cardiac systems.[4]
The concept of Renal impairment in scientific sources
Renal impairment, as described in the text, is a condition where the kidneys don't function correctly, impacting drug dosage, metabolism, and excretion. It can be a side effect of certain medications and a factor in other conditions, requiring careful monitoring and dose adjustments to prevent complications.
From: The Malaysian Journal of Medical Sciences
(1) Renal impairment raises concerns regarding the systemic accumulation of Apixaban because this specific drug is only partially cleared from the body through the kidneys, necessitating careful consideration for dosing.[5] (2) Patients with chronic diseases, hepatitis, diabetes, renal impairment, cardiovascular comorbidities, neurological psychiatric disorders were excluded.[6] (3) On day two after admission, the patient experienced septic shock with renal impairment and metabolic acidosis.[7]
From: South African Journal of HIV Medicine
(1) If the exposed person has diminished kidney function, an alternative antiretroviral medication like zidovudine might need to be considered for inclusion in the preventative regimen, despite its own known side effects.[8] (2) Renal impairment due to renal tubular toxicity is a major adverse effect of amphotericin B deoxycholate, typically occurring during the second week of treatment, and it is important to take preventative measures.[9] (3) This is a condition where the kidneys are not functioning properly, and the study investigated its potential association with a medication.[10]
From: African Journal of Primary Health Care and Family Medicine
(1) Increasingly premature infants survive, including many born well before nephrogenesis is complete, and those surviving have evidence of renal impairment that may be subtle.[11] (2) This refers to a condition where the kidneys are not functioning properly, and it was monitored during amphotericin B treatment due to its potential nephrotoxic effects.[12]
From: South African Family Practice
(1) The use of non-steroidal anti-inflammatory drugs (NSAIDs) should be avoided in patients with this.[13] (2) This is a condition in which the use of non-steroidal anti-inflammatory drugs should be avoided; sepsis is a relative contraindication to neuraxial anaesthesia.[14] (3) Renal impairment is marked by microalbuminuria, and it is an early marker for renal impairment in hypertension, so screening for microalbuminuria is recommended in diabetic patients.[15]
From: International Journal of Pharmacology
(1) This can be induced in rats by gentamicin and piroxicam, leading to elevated serum creatinine and urea levels, which indicates impaired kidney function.[16] (2) Dosage adjustment is required for patients suffering from this as the drug mostly gets eliminated through the renal pathway.[17] (3) Salt-sensitive rats with the Nox4 gene deletion demonstrated a reduction in salt-induced hypertension and renal impairment after 21 days.[18]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) Renal impairment can result from the higher inflammatory state and fibrotic changes associated with atrial fibrillation, making the kidneys more susceptible to injury.[19] (2) Renal impairment refers to the reduced ability of the kidneys to function properly, and it is considered a potential common denominator in the relationship between hyperuricemia and heart failure.[20] (3) Renal impairment was identified as one of the 'others' post-COVID-19 effects, suggesting potential kidney-related complications.[21]
From: South African Journal of Psychiatry
(1) This is a condition of the kidneys, and caution is advised, with reduced maintenance doses recommended.[22] (2) A condition where caution is advised, and reduced maintenance doses should be used for patients with significant functional issues, as stated in the text.[23] (3) Caution is advised; reduced maintenance doses should be used for patients with significant functional impairment due to renal impairment.[24]
From: International Journal of Pharmacology
(1) However, these elevations in BUN and serum creatinine were notably alleviated in the co-treatment of PIO against DXR treatment causing renal impairment.[25]