Significance of Reactive oxygen species (ROS)
Reactive oxygen species (ROS) are chemically reactive molecules that contain oxygen and can lead to oxidative damage if not properly regulated. These highly reactive molecules are produced as byproducts of metabolic processes and can cause cellular damage, contributing to various diseases, aging, and conditions like hypertension and diabetes. ROS play complex roles in biological systems, having both beneficial and harmful effects depending on their concentrations. Antioxidants are essential in mitigating the adverse effects of ROS on cellular health.
Synonyms: Oxidative species, Reactive species, Superoxide, Oxidative stress
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The concept of Reactive oxygen species (ROS) in scientific sources
Reactive oxygen species (ROS) are highly reactive molecules that result from cellular metabolism, leading to potential oxidative stress and cellular damage, though their harmful effects can be counteracted by antioxidants.
From: The Malaysian Journal of Medical Sciences
(1) Chemically reactive molecules that can lead to oxidative stress and damage to cellular components.[1] (2) Molecules that can induce oxidative stress and may affect cellular functions, including apoptosis, particularly in the context of the 10398 polymorphism.[2] (3) Chemically reactive molecules containing oxygen that can lead to oxidative stress and cellular damage, particularly elevated in diabetes.[3] (4) Reactive molecules that can cause oxidative damage to cells and are implicated in the aging process and neurodegenerative diseases.[4] (5) Molecules produced during chemotherapy and radiotherapy that are involved in the pathogenesis of oral mucositis.[5]