Significance of Rat liver cell
Rat liver cells are central to various scientific investigations. In the realm of Science, they are employed to analyze how substances like sildenafil impact crucial enzymes that govern glucose metabolism. Simultaneously, Health Sciences explores rat liver cells for imidazoline receptors, aiming to determine if these receptors are unique or related to alpha-2-adrenoceptors. Both areas highlight the cell's significance in understanding biological processes and drug interactions.
Synonyms: Hepatocyte, Liver cell,
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The concept of Rat liver cell in scientific sources
Rat liver cells are used in research to understand how substances impact glucose metabolism enzymes. They are also studied for imidazoline receptors, to determine if they are a unique receptor or a subtype of alpha-2-adrenoceptors.
From: International Journal of Pharmacology
(1) Cadmium has been shown to elevate ROS in these, leading to a decrease in the GSH/GSSG ratio.[1] (2) Chlormadinone acetate was reported to form DNA adducts in rat liver in vitro and human hepatocytes in vitro, as well as micronucleus in these cells in vivo.[2] (3) Rat liver cells are investigated for the presence of imidazoline receptors, exploring whether they represent a novel receptor or a subtype of alpha-2-adrenoceptors.[3]
From: Asian Journal of Pharmaceutics
(1) Studies showed that antioxidants are effective in reducing the release of free radicals from alcohol metabolites in these.[4]
From: International Journal of Pharmacology
(1) Rat liver cells are utilized in studies to examine the effects of substances like sildenafil on key enzymes involved in glucose metabolism.[5]