Significance of Pyogenic granuloma
Pyogenic granuloma is a common reactive gingival lesion characterized by an inflammatory hyperplasia that typically arises in response to irritation, trauma, or hormonal changes, particularly during pregnancy. It is identified by its smooth, lobulated, and often bleeding mass of granulation tissue in the oral cavity. This benign, non-neoplastic growth is frequently confused with other lesions, such as peripheral ossifying fibroma and hemangiopericytoma, making accurate diagnosis essential. Overall, pyogenic granuloma represents an exaggerated tissue response to local stimuli.
Synonyms: Skin lesion, Lobular capillary hemangioma, Pregnancy tumor
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The concept of Pyogenic granuloma in scientific sources
Pyogenic granuloma is an inflammatory hyperplasia manifesting as a red, friable lesion in the oral cavity, resulting from infection or irritation, and involves the analysis of mast cells in its development.
(1) In our experience, there were four cases which presented similar to JNA but later turn out to be nasopharyngeal carcinoma (11 yrs. and 14 yrs.), this and chordoma (18 yrs).[1] (2) A type of tumor-like lesion that can mimic malignancy but is benign and commonly associated with the presence of vascularity, as considered during the initial diagnosis of the case.[2] (3) A benign vascular lesion that can be clinically mistaken for aggressive digital papillary adenocarcinoma, leading to diagnostic confusion.[3]