Significance of Protease
Protease, in the context of Ayurveda, refers to enzymes that break down proteins. In science, it is an enzyme that breaks down proteins and is secreted by mast cells. Health Sciences describes protease as an enzyme involved in HIV replication, targeted by inhibitors, and its mutations can lead to drug resistance. Proteases are also released during inflammation, aiding bacteria, and playing roles in inflammatory, degenerative, and industrial processes.
Synonyms: Proteolytic enzyme, Enzyme, Proteolytic enzyme.
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Protease'
In Hinduism, Protease relates to enzymes crucial for protein breakdown. An imbalance of these enzymes, alongside other elements, may contribute to Dushta Vrana, a condition described within the principles of Ayurveda.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) These are enzymes that break down proteins, and an imbalance of these, along with other factors, can contribute to the condition described in Ayurveda as Dushta Vrana.[1]
The concept of Protease in scientific sources
Protease refers to enzymes that break down proteins, vital in diverse biological and industrial contexts. These enzymes are involved in processes like food processing, inflammation, tissue remodeling, and HIV replication. They are also utilized in the extraction of glycosaminoglycans and can be targeted by inhibitors.
From: International Journal of Pharmacology
(1) An enzyme used to digest proteins in the mucosal tissue, aiding in the extraction of glycosaminoglycans.[2] (2) Proteases, along with enzymes, are released from fibroblasts during inflammation, leading to the degradation of the articular matrix and cartilage.[3] (3) This mediator is released during the second phase of carrageenan-induced inflammation, contributing to the formation of edema.[4]
From: South African Journal of HIV Medicine
(1) An enzyme vital for HIV replication, which is targeted by protease inhibitors, and its mutations can lead to drug resistance.[5] (2) This is an enzyme that is involved in the replication of HIV, and the effect of mutations involving protease remains to be determined in the context of HIV transplantation.[6]
From: International Journal of Pharmacology
(1) An enzyme that breaks down proteins, posing a challenge for the stability of peptide-based therapeutic agents.[7] (2) Proteases are secreted by mast cells, and the study found AhR expression in these cells in the prostatic stroma.[8]