Significance of Porphyromonas gingivalis
Porphyromonas gingivalis, a key focus across multiple disciplines, is a Gram-negative bacterium strongly linked to periodontal disease. Ayurveda recognizes it as a specific bacteria, and curcumin has shown antibacterial activity against it. Science highlights its role in protein expression for potential vaccines. Health Sciences extensively details its pathogenic nature, associating it with inflammation, immune responses, and systemic diseases. It is often targeted in studies evaluating antibacterial agents and is found in the oral cavities of those with periodontitis.
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Porphyromonas gingivalis'
In Hinduism, *Porphyromonas gingivalis* is a type of bacteria linked to periodontal disease. Studies examine its response to antimicrobial agents like curcumin and Chaturjaat. These studies aim to understand how to combat this specific pathogen.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) Porphyromonas gingivalis is mentioned in the text in relation to arg-gingipain inhibition and anti-bacterial activity of malabaricone C.[1] (2) This is a specific type of bacteria, which is included in the antimicrobial study, testing the effectiveness of Chaturjaat against this strain.[2]
From: Journal of Ayurvedic and Herbal Medicine
(1) Porphyromonas gingivalis is a specific type of periodontopathic bacteria, and curcumin inhibits its Argand Lys-specific proteinases, showing antibacterial activity.[3] (2) This is a type of bacteria, one of the periodontal pathogens assessed in the study, and it is related to the progression of periodontal disease.[4]
The concept of Porphyromonas gingivalis in scientific sources
*Porphyromonas gingivalis* is a Gram-negative anaerobic bacterium and major pathogen strongly linked to periodontal disease. It's implicated in gum inflammation, immune responses, and tissue destruction. The bacterium is often investigated for its response to treatments and is found in the oral cavities of those with the disease.
From: Asian Journal of Pharmaceutics
(1) It is one of the periodontal pathogens that causes periodontal destruction.[5] (2) In gingivitis, the bacterium this triggers inflammation and leukocyte proliferation, which produces PAD 4.[6] (3) A bacterium associated with periodontal destruction in subjects, according to J Clin Periodontol 2002;29:1023-8.[7]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) Porphyromonas gingivalis is a key pathogen of chronic periodontitis, significantly identified in the brains of patients who have died from Alzheimer’s disease, and its infection in mice models results in brain colonization and increased amyloid plaque production.[8] (2) Porphyromonas gingivalis periodontal and systemic implications are reviewed systematically.[9] (3) Porphyromonas gingivalis is a bacterial species considered a red complex pathogen, and its levels were observed to decrease in tooth 46 after probiotic treatment.[10] (4) Porphyromonas gingivalis is a plaque sample that was collected at baseline and after 1, 2, 4, 12 and 26 weeks; this bacteria was found to be significantly reduced from baseline to 6 months in a-PDT group and to 12 months in LDD group.[11] (5) Porphyromonas gingivalis, also known as P. gingivalis, is a pathogen of periodontal disease that invades blood vessels and spreads bacterial toxins.[12]
From: International Journal of Pharmacology
(1) Porphyromonas gingivalis fimbrial antigen fusion protein is synthesized and assembled in plants, contributing to advancements in protein expression for potential vaccines.[13]