Significance of Porphyromonas gingivalis
Porphyromonas gingivalis is a Gram-negative, anaerobic bacterium recognized as a primary periopathogen in the progression of periodontal disease. It alters normal oral microflora, leading to tissue destruction and is significantly present in periodontal disease cases. Its role in skewing immune responses towards Th17 highlights its pathogenicity. This bacterium's presence correlates with the severity of periodontal tissue damage, making it a crucial focus in research related to chronic periodontitis and the effectiveness of various antimicrobial treatments.
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The concept of Porphyromonas gingivalis in scientific sources
Porphyromonas gingivalis is a Gram-negative anaerobic bacterium linked to chronic periodontitis, targeted by lemongrass antimicrobial activity, and influences immune responses, particularly skewing T cell responses towards Th17 in periodontal disease.
From: Journal of Indian Society of Periodontology
(1) A Gram-negative, obligatory anaerobic bacterium regarded as a primary etiological factor in the progression of periodontitis, often isolated from periodontitis-diseased lesions.[1] (2) A Gram-negative bacterium that is a significant pathogen in periodontal disease and was tested for sensitivity to Amorphophallus paeoniifolius extracts.[2] (3) A bacterium considered a key pathogen in the development of periodontal disease.[3] (4) A key pathogenic bacterium associated with periodontitis that grows in specific pH conditions, contributing to periodontal disease severity.[4] (5) Porphyromonas gingivalis is a periodontal pathogen investigated in this study, found in subgingival plaque of pregnant women and umbilical cord blood of newborns.[5]
From: World Journal of Pharmaceutical Research
(1) A Gram-negative oral anaerobe associated with periodontitis that is targeted by the antimicrobial activity of lemongrass.[6] (2) A bacterial pathogen associated with periodontal disease that influences immune responses and can skew T cell responses towards Th17.[7]
From: AYU (Journal of Research in Ayurveda)
(1) A Gram-negative anaerobic bacterium associated with chronic periodontitis.[8]