Significance of Poor prognosis
Poor prognosis refers to an unfavorable prediction about the course of a disease, indicating a low chance of recovery or survival. It is used across various fields to describe the expected negative outcome of a condition. In Ayurveda, it can indicate a less favorable outcome for certain diseases. In science, it may be linked to factors like advanced disease stages or treatment resistance. Health Sciences uses it to describe the expected outcome of numerous conditions, from cancer to leukemia, highlighting the importance of early detection and intervention.
Synonyms: Unfavorable prognosis, Pessimistic outlook, Negative prognosis, Unfavorable outcome
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Poor prognosis'
In Hinduism, "Poor prognosis" signifies an anticipated unfavorable outcome. It suggests lasting neurological deficits from conditions like stroke, a negative outlook for recovery, or unfavorable signs like a disintegrating oil drop. Neglecting certain conditions can also lead to complications.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) Poor prognosis, or Maranam, is associated with Sannipataj Jwar Lakshanas and is related to MODS, delirium, and septic shock, highlighting the severe outcomes of uncontrolled sepsis.[1] (2) It is a prediction of the likely course of a disease or ailment, and subjects with this were excluded from the study.[2] (3) If the oil drop disintegrates quickly, shows rapid and erratic movements, or sinks immediately, it is often considered an unfavourable sign, indicating a less favorable outcome.[3] (4) This term refers to the expectation of a negative outcome, particularly in the case of diseases like stroke, where the damage to brain tissues may not be fully repaired, leading to lasting neurological deficits.[4] (5) This phrase describes the likely outcome of certain medical conditions mentioned in the chapter, indicating a negative outlook for the patient's recovery or survival.[5]
From: International Research Journal of Ayurveda and Yoga
(1) Diseases with frequent or severe Upadrava are more difficult to cure and indicates a poor prognosis.[6] (2) Negligence and failure to treat the precancerous condition are the main causes behind the chronicity of the disease, resulting in this outcome.[7]
The concept of Poor prognosis in scientific sources
Poor prognosis signifies an unfavorable medical outcome. It indicates a low chance of recovery, survival, or successful treatment, often linked to severe disease stages, advanced conditions, treatment resistance, or delayed diagnosis. It's associated with permanent disability, recurrence, or death.
From: The Malaysian Journal of Medical Sciences
(1) Hypercalcemia is common in malignancy and is one of the predictors of the poor prognosis of primary adrenal lymphoma, making it a significant factor.[8] (2) This can be predicted in lung adenocarcinoma through beta-Catenin/POU5F1/SOX2 transcription factor complex mediates IGF-I receptor signaling.[9] (3) This is the prediction of a negative outcome for a disease, and studies on patients have shown the presence of thrombocytopenia and its association with this.[10] (4) This is a likely outcome for many patients with the condition, specifically when the disease is detected in an advanced stage, leading to a less favorable outlook.[11] (5) This refers to a likely negative outcome of a disease, and cortical involvement in Wernicke's encephalopathy is associated with this, highlighting the importance of early intervention.[12]
From: International Journal of Pharmacology
(1) It indicates a less favorable outlook for a patient's disease, with a higher likelihood of progression or recurrence.[13] (2) The main treatment strategy for Glioblastoma relapse remains problematic resulting in a poor prognosis.[14] (3) A direct result of patients missing the optimal treatment timing, the tumour has usually reached the middle and later stage when BC shows obvious symptoms.[15] (4) Gastric cancer has this characteristic, which is a reason why it is difficult to cure, particularly in Korea.[16] (5) The toxic effects of cisplatin on muscle tissue are closely related to this, poor response to treatment and negative impact on survival.[17]
From: South African Family Practice
(1) Factors suggesting this include early age at onset, high titre rheumatoid factor, young female, elevated ESR/CRP, elevated platelet count and swelling more than 20 joints.[18] (2) The likely course or outcome of a disease or condition, which in the context of the study, is used to describe the outlook for patients undergoing lower limb amputation due to PVD.[19] (3) This is indicated by the presence of extensive oral HIV-associated Kaposi sarcoma and facial lymphoedoema, suggesting a more severe and potentially terminal stage of the illness.[20] (4) This is a result for patients whose symptoms worsen for longer than 24 hours after physical exertion, and it highlights the impact of activity on the condition.[21] (5) This is the likely course of a disease or medical condition, and is associated with acute heart failure, with high rates of hospital admission and high mortality rates.[22]
From: Asian Journal of Pharmaceutics
(1) It is a prediction of an unfavorable outcome or course of a disease.[23] (2) An outlook that has improved with the development of drugs, medical, and social support, allowing most patients to live independently outside the hospital.[24] (3) An unfavorable outcome of COVID-19, influenced by diabetes and other factors.[25] (4) Glioblastoma Multiforme (GBM), a highly infiltrative grade IV primary malignant brain tumor, is characterized by poor prognosis.[26]
From: South African Journal of Physiotherapy
(1) This is a prediction of a negative outcome, and it can be indicated by certain electrodiagnostic test results.[27] (2) The likelihood of an unfavorable outcome, and aphasia is a serious condition, and the patient is given every opportunity for speech re-education even if prognosis is poor.[28] (3) A condition that can be determined by presenting features in acute lymphocytic leukaemia, in this case a more intensive course of chemotherapy is given.[29]
From: Journal of Public Health in Africa
(1) The poor outcome of cicatricial Retinopathy of Prematurity is highlighted in the study, emphasizing the need for focused training on Retinopathy of Prematurity during ophthalmic and pediatric residency training, and targeted training of trainers.[30]
From: South African Journal of HIV Medicine
(1) This describes the likely outcome of a medical condition, such as KS-associated chylothorax, indicating a challenging health outlook for the patient.[31]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) Poor prognosis is associated with higher expression of CDK 1 and CDC 20 in CRC patients, as evidenced by integrated bioinformatics analysis, which emphasizes their roles.[32] (2) Poor prognosis is associated with ovarian clear cell carcinoma, as it often occurs in younger women and demonstrates worse outcomes compared to similar stages of other histotypes of EOC.[33] (3) It describes the potential for adverse outcomes and recurrent cardiovascular events after experiencing acute coronary syndrome.[34] (4) Indicates an unfavorable prediction of the course of a disease, where poorly differentiated cells of LADC were found in patients.[35] (5) Higher HAMP expression levels in tumor tissues including KIRC, which were related to in terms of OS, DSS and PFI, as revealed by this study.[36]
From: South African Journal of Psychiatry
(1) An unfavorable prediction about the likely course of a disease or condition, which is often associated with the concurrent use of cannabis and psychotic disorders.[37] (2) This refers to the unfavorable outlook for individuals who do not consistently take their prescribed medications, leading to worse outcomes.[38]
From: International Journal of Pharmacology
(1) An unfavorable outlook for a patient's disease, often linked to factors like advanced stage or treatment resistance.[39] (2) Poor prognosis in cancer refers to a less favorable outcome, which in hypopharyngeal squamous cell carcinoma has been correlated with aberrant expression of beclin-1 and LC3.[40]