Significance of Pharmacological target
Pharmacological targets, according to the provided texts, are specific sites, molecules, or pathways within the body that drugs interact with to produce therapeutic effects. These targets can include genes, receptors, enzymes, or pathways involved in disease processes. Understanding these targets is crucial for developing effective treatments, as drugs are designed to influence these specific biological components. Examples include targets for cardiovascular diseases, depression, epilepsy, and COVID-19, demonstrating the diverse applications of pharmacological targeting.
Synonyms: Therapeutic target, Drug target, Biological target, Target receptor, Molecular target, Receptor
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Pharmacological target'
In Hinduism, the pharmacological target signifies the precise bodily locations where medications take effect. Comprehending these targets, facilitated by molecular interactions, is vital for understanding drug pathways and actions within the body.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) These are the specific sites within the body where drugs exert their effects, and understanding these targets is crucial in knowing the pathways and actions of drugs, aided by molecular association.[1]
The concept of Pharmacological target in scientific sources
Pharmacological targets are specific molecules or pathways in the body, like receptors or enzymes, that drugs interact with to produce therapeutic effects. These targets, crucial in disease processes, include viral entry mechanisms and immune regulation, which may be affected by drugs such as benzimidazoles or Dalfampridine.
From: International Journal of Pharmacology
(1) Medicinal plant drug discovery continues providing new and important leads to these various sites.[2] (2) Specific biological processes or molecules within the body that are affected by the action of herbs, influencing the healing of wounds.[3] (3) The text identifies TLRs as pharmacological targets for plant-derived compounds in infectious and inflammatory diseases.[4] (4) Tumor angiogenesis can be considered an important pharmacological target for cancer prevention and treatment according to the text.[5] (5) Pharmacological targets are specific molecules or pathways within the body that are influenced by the active components of Gastrodiae rhizoma, playing a crucial role in mediating its therapeutic effects against depression.[6]
From: Asian Journal of Pharmaceutics
(1) The study should be conducted on these, which provides a targeted search for the creation of new drugs.[7] (2) It is to reduce overall dosage and cost while optimizing therapeutic efficacy of the microparticulate delivery systems.[8] (3) Studying has to be carried out on these targets, in vivo and in vitro models.[9] (4) Defective mechanisms of DNA repair in tumor cells are used as this for cancer treatment.[10] (5) A more detailed definition of the role of this system will provide insights into new pharmacological targets for the treatment of atherosclerosis, diabetes mellitus, cancer, obesity, coronary heart disease, retinopathy, etc.[11]
From: The Malaysian Journal of Medical Sciences
(1) This refers to TrkB and IP3 as potential targets for anti-epilepsy drugs, based on their neuroprotective roles in the context of epilepsy.[12]
From: International Journal of Pharmacology
(1) Pharmacological targets are specific molecules or pathways in the body that drugs can interact with to produce a therapeutic effect.[13] (2) Genes associated with the molecular response of the brain to heat stress that could be targeted for therapeutic interventions.[14] (3) These are specific molecules or pathways within the body that drugs can interact with to produce a therapeutic effect.[15]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) Specific molecules or pathways in the body that are affected by drugs, leading to therapeutic or adverse effects.[16] (2) While addressing diets seem more feasible compared to developing new these, dietary monitoring connects physiological pathways in the complex human body with positive effects.[17] (3) These are specific molecules or pathways in the body that drugs are designed to affect, and combination therapy can target multiple of these simultaneously.[18]