Significance of Peripheral ossifying fibroma
Peripheral ossifying fibroma is a benign reactive hyperplasia that occurs exclusively in the gingiva, characterized by mineralized tissue. This non-neoplastic lesion typically arises in the maxillary anterior region and is thought to originate from the periodontal ligament's connective tissue. Commonly affecting young adults, especially females, POF presents as a well-defined growth in the gum tissues, often linked to irritation or trauma. It accounts for approximately 9% of all gingival lesions and is marked by slow growth and unique histopathological features.
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The concept of Peripheral ossifying fibroma in scientific sources
Peripheral ossifying fibroma is a benign hyperplastic gingival lesion characterized by mineralized tissue, primarily affecting the anterior maxilla in women, and arising from the interdental papilla as a pedunculated mass.
(1) A reactive gingival lesion with mineralization tendencies that can mimic other conditions.[1] (2) Another condition that can resemble irritational fibroma clinically and is included in the differential diagnosis.[2] (3) A non-neoplastic, reactive lesion of the gingiva, primarily seen in the maxillary anterior region, suggested to originate from the connective tissue of the periodontal ligament.[3] (4) A reactive lesion commonly found in the gum tissues that has been used interchangeably in references with peripheral odontogenic fibroma, though they have different origins and biological behaviors.[4] (5) A benign mass that arises from mesenchymal cells in the periodontal ligament and necessitates presence within gingival tissue for diagnosis.[5]
(1) A reactive hyperplastic inflammatory lesion that is a non-neoplastic gingival lesion affecting mostly the anterior portion of the maxilla in women, often appearing as a well-defined, pedunculated mass.[6]