Significance of Peptide Sequence
Peptide sequence analysis plays a crucial role in protein identification and vaccine development. Digestion processes yield unique sequences analyzed by mass spectrometry to identify proteins like GLP-1 R and ALR. The vaccine rindopepimut utilizes peptide sequences to stimulate immune responses. Certain sequences also enhance cellular uptake of molecules. These applications highlight the significance of peptide sequence analysis in diverse biological and therapeutic contexts.
Synonyms: Amino acid chain, Polypeptide, Protein sequence, Peptide chain, Amino acid sequence
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Peptide Sequence in scientific sources
Peptide sequence, crucial for vaccine development (rindopepimut), protein identification (GLP-1 R, ALR via Mascot), and proteome analysis (MALDI-TOF), arises from digestion and enables cellular uptake of molecules.
From: Asian Journal of Pharmaceutics
(1) The vaccine rindopepimut (CD 110) consists of this that enables a potent immune response against EGFRvIII.[1] (2) These sequences are known for their ability to facilitate cellular uptake of various cargo molecules.[2] (3) The sequence was searched in Mascot search engine, and flavin adenine dinucleotide (FAD)-linked sulfhydryl oxidase ALR was found.[3] (4) This was searched in Mascot search engine, and GLP-1 R was found.[4]
From: International Journal of Pharmacology
(1) These are analyzed by MALDI-TOF peptide analysis system to identify proteins in proteome spots after lithium induction.[5] (2) The digestion process of peptides using trypsin leads to produce different sequences of peptides.[6]