Significance of Particle size
Particle size, across Ayurveda, Science, Health, and Environmental Sciences, refers to the dimensions of individual particles within a substance. It influences absorption, delivery, and efficacy in medicine; gas desorption and diffusion in environmental science; and cellular uptake in health science. Measurement techniques vary, but smaller particle sizes generally enhance dissolution, penetration, and bioavailability, making it a crucial factor in formulation and effectiveness.
Synonyms: Grain size, Particle diameter, Size of particles, Granule size, Pellet size, Aggregate size, Fragment size
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Particle size'
In Hinduism, particle size refers to the dimensions of medicinal substances, especially Bhasmas, often measured in nanometers. Reducing particle size through processes like Shodhana and Mardana enhances absorption, bioavailability, and therapeutic efficacy.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) Particle size reduction occurs during Kharaliya Rasayan, where continuous and repeated rubbing action helps in reduction of particle size.[1] (2) Mardana helps in reduction of this measurement, thereby ensuring a faster assimilation of the drug inside the body.[2] (3) Due to a certain process, this of the formulation may be reduced.[3] (4) The reduction of particle size is a significant aspect of the process, contributing to improved absorption and efficacy of the material within the body's systems.[4] (5) Particle size is of great value in the field of medicine and influences dosage, delivery, and penetration of the medicine, varying from macro to nano scale.[5]
From: International Research Journal of Ayurveda and Yoga
(1) SEM analysis shows that in each and every stage this is reducing and which makes the drug more absorbable.[6]
From: Journal of Ayurvedic and Herbal Medicine
(1) This refers to the size of the material particles, which decreases as the number of puta increases, which is crucial in determining the bioavailability.[7] (2) This is the measurement of the dimensions of particles within a substance, such as Haratal Bhasma or Rasamanikya, determined using techniques like TEM.[8] (3) This is a factor that, when reduced, enhances absorption, with all the chemical changes making the material more body-friendly, as part of the Shodhana process.[9] (4) This is a measurement of the dimensions of the individual particles within the formulation, which was found to be different depending on the preparation method used.[10]
The concept of Particle size in scientific sources
Particle size significantly impacts drug absorption, dissolution, and release, especially in nano and micro-formulations. It affects bioaerosol behavior, adsorption, UV filtering, and influences the efficacy of various pharmaceutical and herbal applications.
From: International Journal of Pharmacology
(1) Particle sizes of Coptis chinensis roots and rhizomes granules influence picroside content, with smaller particle sizes generally increasing the extraction yield.[11] (2) This refers to a distribution range between 30 and 500 nm with an average nanoparticles size around 53.50 nm.[12] (3) The size of the microspheres were determined using an optical microscope.[13]
From: Asian Journal of Pharmaceutics
(1) The measurement of the vesicles' diameter, which was independent of surfactant and uniform due to sonication.[14] (2) The influence of particle size of liposomes on the deposition of drug into skin.[15] (3) The physical dimension of individual particles in a powder or dispersion.[16]
From: South African Family Practice
(1) This is a major determinant of the proportion of drug that reaches the lung, playing a critical role in the optimal treatment of asthma, according to the provided text.[17]
From: Journal of Public Health in Africa
(1) Particle size is a characteristic of the NLC, and the study indicates that smaller particle sizes of NLC-AMS oil have greater hair growth activity.[18] (2) The measurement of the dimensions of the particles in a formulation, which was determined using the Dynamic Light Scattering method.[19]
From: The Malaysian Journal of Medical Sciences
(1) The dimension of dust particles, which is a factor that could influence the lack of significance observed in the current study.[20]
From: Sustainability Journal (MDPI)
(1) Particle size is a critical parameter in the shredding process, as it determines the fineness of the shredded e-waste materials for further processing.[21] (2) Particle sizes of road dust are a factor that can influence the behavior and health effects of heavy metals, and future research may investigate these effects more closely.[22] (3) The silica structure and particle size of RHA are crucial in determining the optimal cement replacement level, rather than just the overall silica content.[23]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) The physical dimension of particulate matter, a crucial factor determining its ability to enter the body and its association with various health problems.[24] (2) Particle size of soil polluted by gold mining was analyzed to understand the distribution of heavy metals, demonstrating how physical characteristics of the medium affect contaminant behavior.[25] (3) Filtration efficiencies increased with this, and diffusion efficiency weakened while interception and inertial efficiencies increased as it got larger.[26]
From: International Journal of Pharmacology
(1) A significant characteristic that influences how particles adhere to material surfaces, with smaller particles adhering more strongly.[27] (2) The mushroom samples were ground down to approximately 1 mm to facilitate the fatty acid analysis procedure.[28] (3) Particle size reduction is a primary goal of milling in pharmaceutical processing, aiming to enhance dissolution rates, particularly for insoluble drugs.[29]