Significance of Oxidative stress
Oxidative stress is a condition characterized by an imbalance between the production of free radicals and the body's antioxidant defenses, leading to cellular damage. This state can result from excessive free radicals and is implicated in various health issues, including neurodegenerative diseases like Alzheimer's, liver injury, and diabetes-related complications. The detrimental effects of oxidative stress are linked to various diseases, highlighting the importance of antioxidants in protecting against cellular damage and maintaining overall health.
Synonyms: Oxidative damage, Free radical injury, Cellular stress, Free radical damage, Oxidative burden
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Oxidative stress in scientific sources
Oxidative stress is an imbalance between free radicals and antioxidants that leads to cellular damage, contributing to conditions like cardiovascular diseases, Alzheimer's, diabetes, and various degenerative diseases, exacerbated by factors such as xenobiotic exposure and diet.
From: World Journal of Pharmaceutical Research
(1) A harmful condition resulting from the imbalance between free radicals and antioxidants in the body, which chalcones can help counteract.[1] (2) A condition characterized by excessive free radicals attacking cells in the body leading to damage, which is often implicated in various diseases including cardiovascular disorders.[2] (3) A condition characterized by excessive free radicals in the body; HCA in Garcinia cambogia helps to inhibit oxidative stress.[3] (4) An imbalance between free radicals and antioxidants in the body, contributing to inflammation and metabolic disorders.[4] (5) An imbalance between free radicals and antioxidants in the body, which can lead to cellular damage and disease.[5]
From: International Ayurvedic Medical Journal
(1) A condition resulting from excessive free radicals causing cellular damage, influencing the progression of NAFLD.[6] (2) A condition characterized by increased levels of reactive oxygen species, which can lead to cellular damage, particularly in liver cells during acetaminophen overdose.[7] (3) An imbalance between free radicals and antioxidants in the body, which can lead to cellular damage and is implicated in many chronic diseases, including hyperlipidemia.[8] (4) An imbalance between free radicals and antioxidants in the body, leading to cellular damage that can impact fertility.[9] (5) A form of stress implicated in chronic diseases, which Rasayana therapy is suggested to help manage, highlighting its importance in Ayurvedic medicine.[10]
From: Journal of Ayurveda and Integrative Medicine
(1) A condition resulting from an imbalance between reactive oxygen species (ROS) and antioxidants in the body, often leading to cellular damage and associated with conditions like cancer.[11] (2) A condition characterized by excessive reactive oxygen species (ROS) which can lead to cellular damage.[12] (3) A harmful condition generated by alcohol consumption that can lead to liver inflammation and complications, and which the study aimed to counteract with GT extracts.[13] (4) Oxidative stress is presented as a predominant factor in endothelial dysfunction, contributing to the development of cardiovascular diseases.[14] (5) An imbalance between free radicals and antioxidants in the body, which can lead to cellular damage and is involved in the pathophysiology of many diseases including MetS.[15]
From: The Malaysian Journal of Medical Sciences
(1) A condition characterized by excessive free radicals in the body, contributing to neuronal damage following stroke.[16] (2) A condition resulting from an imbalance between free radicals and antioxidants in the body; certain extracts from Terminalia spp. are noted for their antioxidant activity.[17] (3) An imbalance between free radicals and antioxidants in the body, which can contribute to aging and various health conditions, including sarcopenia.[18] (4) A condition resulting from an imbalance between free radical production and antioxidant defenses, implicated in various diseases and conditions related to bone health.[19] (5) A pathophysiological condition caused by an imbalance between reactive oxygen species production and antioxidant defenses, implicated in the pathogenesis of Parkinson's disease.[20]
From: AYU (Journal of Research in Ayurveda)
(1) A pathological condition resulting from an imbalance between reactive oxygen species production and the capability of the cellular antioxidant system.[21] (2) A condition associated with certain genes found in a Pitta-predominant subgroup of rheumatoid arthritis patients.[22] (3) A condition resulting from an imbalance between free radicals and antioxidants in the body, often exacerbated by chronic stress.[23] (4) A condition in which free radicals overwhelm antioxidant defenses, implicated in the pathology of cataract development.[24] (5) A condition characterized by excessive free radicals, which can lead to cell damage; antioxidants help mitigate this effect.[25]
From: Journal of Indian Society of Periodontology
(1) A condition resulting from an imbalance between free radicals and antioxidants, contributing to the severity of periodontal disease.[26] (2) A harmful condition arising from an imbalance between free radicals and antioxidants in the body, leading to cellular damage and chronic inflammation.[27] (3) A condition resulting from the imbalance between reactive oxygen species (ROS) and antioxidants, contributing to tissue damage and various systemic diseases.[28] (4) A condition characterized by increased levels of reactive oxygen species leading to potential damage to cells, specifically examined through the levels of cytokines during orthodontic treatment.[29] (5) A condition arising within tissues when there is an imbalance between reactive oxygen species generation and antioxidants, often leading to cellular damage.[30]
From: Ancient Science of Life
(1) A condition caused by an imbalance between free radicals and antioxidants in the body, leading to potential cellular damage.[31] (2) A state in living organisms characterized by excessive production of free radicals, which can lead to cellular damage and contribute to various chronic diseases.[32] (3) Oxidative stress refers to an imbalance between free radicals and antioxidants in the body, which can lead to cellular damage and contribute to aging.[33] (4) A condition resulting from an imbalance between pro-oxidants and antioxidants in the body, contributing to many diseases and addressed by plant antioxidants.[34] (5) An imbalance between free radicals and antioxidants in the body, leading to cellular damage.[35]
From: Ayushdhara journal
(1) A state induced by muscle damaging exercise that can lead to health complications and impaired recovery.[36] (2) An imbalance in the body due to excess free radicals that contribute to the damage in cancer patients, which Rasayana aims to mitigate.[37] (3) A condition resulting from excessive reactive oxygen species, posing a health risk for astronauts in space environments.[38] (4) A condition arising due to the excessive production of free radicals and insufficient antioxidants, leading to cellular damage, particularly in liver tissues.[39] (5) A condition arising due to the imbalance between free radicals and antioxidants in the body, contributing to degenerative diseases like cervical spondylosis.[40]
From: Journal of Ayurveda and Holistic Medicine
(1) An imbalance between free radicals and antioxidants in the body, leading to cellular damage.[41] (2) Oxidative stress is a condition caused by an imbalance between free radicals and antioxidants in the body, which can be exacerbated by exposure to xenobiotics.[42] (3) An imbalance between free radicals and antioxidants in the body, contributing to various health issues, including complications from varicose veins.[43] (4) An imbalance between free radicals and antioxidants in the body, leading to potential cell damage.[44] (5) An imbalance between free radicals and antioxidants in the body, which is considered a contributing factor to complications associated with diabetes.[45]