Significance of Oxidative stress
Oxidative stress is defined as an imbalance between free radicals and antioxidants in the body, leading to cellular damage. This condition is implicated in various diseases across different fields, including neurodegenerative disorders, liver damage, diabetes, and even environmental toxicities. Factors like unhealthy diets, stress, pollution, and certain chemicals can induce it. Practices like yoga, herbal remedies, and specific compounds show promise in reducing oxidative stress by improving the body's antioxidant defenses.
Synonyms: Oxidative strain, Oxidative damage, Free radical injury, Redox imbalance, Cellular stress, Free radical damage, Oxidative burden
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Oxidative stress'
In Hinduism, oxidative stress signifies an imbalance between free radicals and antioxidants, causing cellular damage and disease. It's linked to diabetes, inflammation, and other conditions, and can be mitigated through herbs, yoga, and dietary adjustments.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) A condition induced by doxorubicin in mice, against which the root extract of Hemidesmus indicus has a cardioprotective effect.[1] (2) This is one of the pathophysiological processes involved in POAG progression, which may be addressed with adjunctive treatments.[2] (3) Kodo millet is versatile in various dishes and may also combat this condition, contributing to its health benefits.[3] (4) A state of imbalance between free radicals and antioxidants in the body, implicated as a factor in the pathophysiology of Polycystic Ovarian Syndrome.[4] (5) Flavonoids act by inducing oxidative stress within fungal cell wall, which is one of the mechanisms of action described in the provided text.[5]
From: International Research Journal of Ayurveda and Yoga
(1) An imbalance of free radicals and antioxidants in the body, which yoga may help modulate, contributing to improved health outcomes.[6] (2) Yoga aims at reducing the toxic buildup of reactive oxygen species and consequent damage from it, reducing inflammatory signaling through the proinflammatory NF-κB-related gene expression.[7] (3) It causes damage and prevents the effective uptake of apoptotic cells by macrophages, hindering organ repair processes.[8] (4) This can lead to cell and tissue damage and contribute to chronic conditions.[9] (5) This is the primary cause of CVDs, and certain fruits can play a role in treatment.[10]
From: Journal of Ayurvedic and Herbal Medicine
(1) This is an imbalance between the production of reactive oxygen species and the ability of the body to counteract their harmful effects, leading to cell damage, including liver injury, as mentioned in the text.[11] (2) The study investigates the ability of Tinospora cordifolia to reduce oxidative stress and the disruption of carbohydrate metabolism in rats with experimentally induced type 2 diabetes.[12] (3) An imbalance in the body caused by an excess of free radicals and a deficiency of antioxidants, which can lead to cellular damage and contribute to various health problems.[13] (4) This is an imbalance between the production of reactive oxygen species and the ability of the body to neutralize them, and it is involved in the development of diabetic peripheral neuropathy in STZ-induced diabetic rats.[14] (5) Oxidative stress occurs when there is an imbalance between the production of free radicals and the body's ability to neutralize them, potentially leading to various health issues.[15]
The concept of Oxidative stress in scientific sources
Oxidative stress is an imbalance between free radicals/reactive oxygen species and antioxidants, leading to cellular/tissue damage. It's implicated in diseases like diabetes, toxicity, dementia, liver damage, myocardial infarction, and kidney injury, and is linked to factors like UV exposure and exercise.
From: International Journal of Pharmacology
(1) This is a condition that can be regulated by antioxidant enzymes and low concentrations of chemical agents including antioxidants.[16] (2) The results of the present study provide an important basis for the use of methanol extract from the stem bark of Alafia multiflora for the management of this.[17] (3) A comprehensive review of biochemical and molecular evidences from animal and human studies.[18] (4) This is linked to ischemic heart disease and treatment therapies with antioxidant or free radical scavenging action may help reduce it.[19] (5) Nicotine enantiomers cause this, according to the text.[20]
From: Asian Journal of Pharmaceutics
(1) A condition that gastric epithelial cells infected with H. pylori are able to induce.[21] (2) The anticancer effects of p-coumaric acid include reduction of this.[22] (3) Lipid peroxidation (a), glutathione (GSH) (b), and catalase (c) were performed of the subjects from both groups to observe the oxidative stress in liver tissue with the progression of disease.[23] (4) Overview of studies examining the roles of this and free cellular iron.[24] (5) An imbalance between the production of free radicals and the body's ability to neutralize them, potentially leading to cellular damage and inflammation.[25]
From: The Malaysian Journal of Medical Sciences
(1) Weight gain has been reported to increase systolic and diastolic blood pressure, triglycerides and this.[26] (2) This is a condition of the central nervous system, and it is discussed in the context of malaria, and its integrated response to the disease.[27] (3) This is an imbalance between the production of reactive oxygen species and the body's ability to neutralize them, and the study investigated the effects of Zamzam water on this imbalance.[28] (4) Oxidative stress is a condition where the mazF9 toxin gene is expressed, mimicking host's defense mechanisms that pathogen encounters during infections in humans.[29] (5) This refers to an imbalance in the body's production of reactive oxygen species and its ability to detoxify them, potentially leading to cellular damage and is an important element in the production of secondary complications in DM.[30]
From: Journal of Medicinal Plants for Economic Development
(1) This is an imbalance between free radicals and antioxidants in the body.[31] (2) This is an imbalance between the production of free radicals and the body's ability to neutralize them, which can damage cells and tissues and is linked to various health problems, including erectile dysfunction.[32] (3) This is associated with increased production of oxidising species or a significant decrease in the effectiveness of antioxidant defences and can result in numerous diseases and disorders.[33] (4) This is experienced by explants treated with lower concentrations of plant growth regulators, based on the accumulation of malondialdehyde concentration.[34] (5) This is a state that can lead to the development of many degenerative diseases, including diabetes and its complications, resulting from an increased production of free radicals within the body system.[35]
From: Onderstepoort Journal of Veterinary Research
(1) This is an imbalance of free radicals and antioxidants in the body, and it can affect the survival of bacteria.[36] (2) This is the damage caused by reactive oxygen species, and certain virulence factors may help bacteria tolerate oxidative stress, promoting their survival within the host.[37] (3) An imbalance in the body caused by excessive production of reactive oxygen species or the inadequate function of antioxidant defenses, leading to potential cell damage.[38] (4) A condition in which there is an imbalance between the production of free radicals and the ability of the body to counteract or detoxify their harmful effects, is examined in lambs infected by Haemonchus contortus.[39] (5) This refers to an imbalance in the body caused by an excess of reactive oxygen species, and the text mentions that trace minerals, including selenium, play a role in supporting antioxidant defense mechanisms.[40]
From: Journal of Public Health in Africa
(1) It can cause nuclear factor-kB activation according to Biochemical Pharmacology.[41] (2) This is an imbalance in the body between the production of free radicals and the ability of the body to counteract their harmful effects.[42] (3) This is the damage to the skin caused by free radicals, which can be prevented by the antioxidant properties of the hand gel's ingredients.[43] (4) Oxidative stress can be accelerated by smoking and may increase the risk of dementia, leading to senile plaque and neurofibrillary tangles formation.[44] (5) This is a condition caused by an imbalance in the production of reactive oxygen species, which can lead to cell injury and is linked to various diseases, including those related to the brain.[45]
From: South African Family Practice
(1) This occurs due to an imbalance between the production of reactive oxygen species and the ability of an organism to repair such damage, according to the text.[46] (2) This plays an important role in cholesterol metabolism, where oxidized LDL is toxic to the vascular network, and high-density lipoprotein acts as an antioxidant, and it is believed to be a major cause of plaque rupture and thrombosis.[47] (3) Oxidative stress is increased when the production rate of ROS/RNS overpowers the endogenous antioxidant defence system’s neutralising ability, resulting in cellular dysfunction and muscle damage, and is an adverse effect of exercise-induced oxidative stress.[48] (4) This is a process affected by Angiotensin II, and is reduced by bradykinin, which is a protective effect of ACE inhibitors.[49] (5) Oxidative stress leads to endothelial dysfunction, and then erectile dysfunction, and it is caused by atherosclerosis, smoking, diabetes, and hypertension.[50]
From: Journal of Metabolic Health
(1) Oxidative stress is an imbalance between the production of free radicals and the ability of the body to counteract or detoxify their harmful effects, potentially impacting neuronal function.[51] (2) An increase in the polyol pathway can lead to this by depleting NADPH when glucose is first converted to sorbitol in the first step of the pathway, leading to complications.[52] (3) The study indicates how this is suppressed by beta-hydroxybutyrate, an endogenous histone deacetylase inhibitor, highlighting its benefits.[53] (4) Oxidative stress is reduced by yoga, lowering the levels of malondialdehyde (MDA), interleukin 6 and leptin, and improving the levels of adiponectin, which is a mechanism behind its efficacy.[54] (5) The resulting instance of this leads to eventual mitochondrial dysfunction or destruction, which has been implicated in the pathology or progression of conditions not typically associated with insulin resistance.[55]
From: South African Journal of HIV Medicine
(1) This phrase describes the imbalance between the production of reactive oxygen species and the body's ability to neutralize them, which can lead to cellular damage.[56] (2) This is associated with endothelial activation and arterial stiffness, as highlighted by the research conducted on individuals with treated HIV in Zambia.[57] (3) Oxidative stress is a condition that is related to higher levels of reactive oxygen species and circulating pro-inflammatory cytokines, commonly increased in persons living with human immunodeficiency virus.[58] (4) This phrase is associated with diabetes and dyslipidaemia, independently of inflammation in long-term antiretroviral-treated HIV-infected patients.[59] (5) Cellular stress is comprised of various processes that are additive, such as oxidative stress, cell response to DNA damage, mitochondrial stress, formation of an intracellular network of signalling pathways of cellular stress, and formation of pro-inflammatory receptor and secretory cell phenotype.[60]
From: South African Journal of Physiotherapy
(1) This is considered in the context of septic shock and disseminated intravascular coagulation, which may contribute to the damage of cells and tissues in the body.[61]
From: International Journal of Pharmacology
(1) Oxidative stress, specifically cisplatin-induced renal oxidative stress in rats, can be inhibited by crocin.[62] (2) A condition characterized by increased reactive oxygen species and elevated Malondialdehyde (MDA) concentration, which can be counteracted by green tea and its constituents through increased antioxidant capacity and reduced lipid peroxidation.[63] (3) A condition that can be induced by substances like thioacetamide and is potentially affected by antidepressant drugs.[64] (4) An imbalance between free radicals and antioxidants in the body, which pesticides can induce, leading to health problems.[65] (5) A state where there is an overproduction of reactive oxygen species, leading to cellular damage and contributing to the pathogenesis of various diseases.[66]
From: International Journal of Pharmacology
(1) A condition that can be reduced by Amla (Emblica officinalis Gaertn.) extracts in diabetic rats.[67] (2) This is an imbalance in the production of reactive oxygen species and the body's ability to neutralize them, which was addressed by baicalein's antioxidant properties.[68] (3) This is a factor that contributes to the progression of diabetic cataracts, and rutaecarpine has shown valuable activity in this case as well.[69]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) Some evidence suggests that exposure to PM induces chronic inflammation and this, which may contribute to the pathogenesis of ADHD.[70] (2) It is a crucial mechanism of 1,4-benzoquinone toxicity and hematotoxicity in the bone marrow, which can be measured via specific profiles.[71]
From: South African Journal of Psychiatry
(1) This is a condition that is implicated in neuroleptic-induced tardive dyskinesia, and the text discusses the role of reactive oxygen species and antioxidants in this disorder.[72] (2) This term refers to differences in markers found in Western literature, which have been implicated in causation within a vulnerable group, according to the provided text.[73] (3) An imbalance in the body that can damage cells, is considered a major contributor to the progression of Parkinson's disease.[74]