Significance of Nuclear receptor
Nuclear receptor refers to a class of proteins located in cells that respond to steroid hormones and other signaling molecules, mediating important biological processes such as gene expression and inflammation. These receptors, which bind to specific DNA sequences, play a crucial role in initiating gene transcription upon ligand attachment. Beyond their known association with hormones like estrogen and progesterone, nuclear receptors are also implicated in various conditions, including breast cancer biology, due to their regulatory functions in gene expression.
Synonyms: Nr, Transcription factor, Steroid receptor
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The concept of Nuclear receptor in scientific sources
Nuclear receptors are proteins in cells that react to steroid hormones and related molecules, playing a crucial role in influencing various biological processes, such as inflammation, according to regional sources.
From: The Malaysian Journal of Medical Sciences
(1) This is a protein that binds to specific DNA sequences, and is involved in the regulation of gene expression and it forms a regulatory loop, as mentioned in the provided information.[1]