Significance of Normal cells
Normal cells are defined as cells that function healthily without abnormal growth, exhibiting typical characteristics and morphology. They serve as a baseline for comparisons, demonstrating features like uniform nuclear membranes and distinct nucleoli. Unlike cancer cells, normal cells, such as 3T3 and Chang liver cells, do not show oncolytic effects when exposed to certain viruses and are less susceptible to anticancer enzyme-induced starvation due to their distinct metabolic processes. Normal cells are essential for understanding healthy bodily functions.
Synonyms: Healthy cells, Somatic cells
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The concept of Normal cells in scientific sources
Normal cells are characterized by their typical growth and healthy functioning, integrating standard cellular functions such as amino acid synthesis, which enhances their resilience against the adverse effects of anticancer treatments.
(1) This refers to the Chang liver cells, which were used as a control to measure the effect of clausine-B.[1] (2) These are cells, such as 3T3 cells, that generally do not show oncolytic effects when exposed to NDV strains, unlike the cancer cells.[2] (3) These are cells that are not cancerous and have different metabolic processes and responses to dietary components compared to cancer cells.[3]