Significance of Non-steroidal anti-inflammatory drugs (NSAIDs)

Non-steroidal anti-inflammatory drugs (NSAIDs) are a class of medications used to alleviate pain, reduce inflammation, and decrease fever. They function by inhibiting the cyclo-oxygenase (COX) enzyme, which reduces prostaglandin synthesis. While effective for conditions like arthritis, NSAIDs can cause side effects such as gastrointestinal irritation and ulcers. Long-term use can also lead to complications.

Synonyms: Non-opioid analgesics

The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.

Hindu concept of 'Non-steroidal anti-inflammatory drugs (NSAIDs)'

Hinduism Books

In Hinduism, Non-steroidal anti-inflammatory drugs (NSAIDs) are medications often used to alleviate osteoarthritis symptoms. However, their prolonged use may lead to negative consequences. This highlights the importance of balance and awareness when using these treatments.

Significance in Ayurveda (science of life):
Ayurveda Books

(1) These are medications commonly used to manage the symptoms of osteoarthritis, but they can have adverse effects with prolonged use.[1]

Ayurveda is a branch of Indian science dealing with medicine, herbalism, taxology, anatomy, surgery, alchemy and related topics. Traditional practice of Ayurveda in ancient India dates back to at least the first millenium BC. Literature is commonly written in Sanskrit using various poetic metres.

The concept of Non-steroidal anti-inflammatory drugs (NSAIDs) in scientific sources

Science Books

Non-steroidal anti-inflammatory drugs (NSAIDs) are a diverse class of medications primarily used to reduce pain, inflammation, and fever. They work by inhibiting the COX enzyme, with various formulations and potential side effects, including gastrointestinal issues.

Significance in Health Sciences:
Health Sciences Books

(1) A class of drugs, including aspirin, that are commonly used but are known to cause gastroduodenal mucosal lesions.[2] (2) Medications used for persistent spasms that can lead to adverse effects like dyspepsia and peptic ulcers with chronic use.[3] (3) A primary risk factor for peptic ulcer disease, with specific types like ibuprofen and naproxen associated with gastrointestinal complications.[4] (4) A class of drugs that exhibit anti-resorptive effects on bone, potentially by inhibiting the COX enzyme, but their impact on bone formation is less clear.[5] (5) These drugs inhibit only peripheral pain mechanisms.[6]

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Significance in Scientific journals, articles, etc.:

(1) A class of drugs that, when used long-term, have been found to reduce the chance of acquiring and delay the onset of Alzheimer's disease.[7] (2) A class of drugs that inhibit both COX-1 and COX-2, often causing side effects, motivating the search for selective COX-2 inhibitors.[8]

(1) A class of drugs that inhibit cyclo-oxygenase, reducing prostaglandin synthesis and possessing analgesic, anti-inflammatory, and antipyretic properties.[9]

This section includes scientific research in the field of healthcare, often involving traditional medicine systems such as Ayurveda, Unani, Siddha and Holistic health. It includes papers from scientific journals classified as either original, clinical or experimental research, review articles or case reports.