Significance of Non Alcoholic Steatohepatitis
Non Alcoholic Steatohepatitis (NASH) is a severe form of non-alcoholic fatty liver disease (NAFLD). It is characterized by fat accumulation, inflammation, and liver cell damage, potentially leading to scarring and cirrhosis. NASH is associated with metabolic disorders like obesity and diabetes and can progress to liver cancer. It is a necroinflammatory disorder and a significant cause of liver-related mortality and morbidity. Research continues to explore its progression and potential treatments.
Synonyms: Fatty liver disease, Nonalcoholic fatty liver disease (nafld), Liver steatosis, Liver inflammation
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Non Alcoholic Steatohepatitis'
In Hinduism, Non Alcoholic Steatohepatitis is a severe form of non-alcoholic fatty liver disease, marked by liver inflammation and potential scarring. It is associated with obesity and diabetes and is a major factor in hepatocellular carcinoma.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) This is a condition representing a part of a wide spectrum of Non Alcoholic Fatty Liver Disease, often associated with factors like obesity and diabetes.[1] (2) This is a condition with inflammation that is a part of non-alcoholic fatty liver disease and a focus of the study.[2] (3) This is a more severe form of fatty liver disease that can develop from hepatic steatosis, which could lead to cirrhosis or hepatocellular carcinoma, as indicated by the text.[3] (4) This is a more severe type of non-alcoholic fatty liver disease, which involves not only excess fat but also inflammation in the liver, potentially leading to scarring.[4]
From: Journal of Ayurvedic and Herbal Medicine
(1) This condition is listed as one of the major causative factors for Hepatocellular Carcinoma.[5]
The concept of Non Alcoholic Steatohepatitis in scientific sources
Non-Alcoholic Steatohepatitis (NASH) is a severe form of NAFLD marked by liver inflammation and damage, potentially leading to cirrhosis and liver cancer. It's linked to metabolic disorders, HIV, and ARV exposure. Treatments are being researched, and it is associated with increased mortality.
From: International Journal of Pharmacology
(1) Non-alcoholic steatohepatitis (NASH) is a necroinflammatory disorder that is part of the spectrum of NAFLD, and it can be found in about one-third of NAFLD cases, with a potential progression to cirrhosis.[6] (2) The text mentions the development of non-alcoholic steatohepatitis and its association with hepatocarcinogenesis in rats.[7] (3) Ursodeoxycholic acid and vitamin E are studied in a trial for non-alcoholic steatohepatitis.[8] (4) A liver condition that may benefit from myricetin, which has shown favorable effects against it.[9]
From: The Malaysian Journal of Medical Sciences
(1) Non-alcoholic steatohepatitis is a disease described in 1980, and it is a poorly understood liver disease that mimics alcoholic hepatitis and may progress to cirrhosis.[10] (2) This is a condition that affects the liver, and it is investigated for its progression in humans and mice, in relation to specific signaling pathways.[11] (3) A severe form of NAFLD that can progress to cirrhosis and liver cancer, with its progression still not fully understood.[12]
From: South African Journal of HIV Medicine
(1) The study notes that a specific liver condition is associated with an increased risk of progression to a more severe form of the disease.[13] (2) Non-alcoholic steatohepatitis (NASH) may result from HIV infection and exposure to the metabolic side effects of ARVs, contributing to liver damage and requiring management.[14]
From: Journal of Metabolic Health
(1) This condition is a potential outcome of fatty liver disease, insulin resistance, and hepatic iron overload.[15]
From: International Journal of Pharmacology
(1) The pathogenesis of non-alcoholic fatty liver disease is not fully understood, and although insulin resistance is a primary pathogenic factor, many other elements are involved in both liver fat accumulation and the slow progression to non-alcoholic steatohepatitis.[16] (2) Non-alcoholic steatohepatitis is a form of chronic liver injury that can trigger the activation of hepatic stellate cells.[17] (3) A liver condition characterized by inflammation and fat accumulation, in which Eriobotrya japonica seed extract has been studied for its effects on oxidative stress.[18]