Significance of Neuroprotective effect
Neuroprotective effect, across Ayurveda, Science, and Health Sciences, describes the ability of substances or treatments to safeguard nerve cells from damage or degeneration. This beneficial action can be achieved through various mechanisms, including protecting against oxidative stress, inhibiting harmful processes, and promoting regeneration. Many compounds, such as those found in herbal extracts, vitamins, and pharmaceuticals, exhibit these effects, potentially benefiting conditions like neurodegenerative diseases, brain injury, and toxicity.
Synonyms: Neuroprotection, Brain protection, Neuroprotective properties, Neuroprotective activity, Neuroprotective influence, Neuroprotective benefit
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Neuroprotective effect'
In Hinduism, "Neuroprotective effect" denotes the capacity of substances, like those in Madhuyashti and Saraswatarishta, to shield neurons from harm. This includes protection against oxidative stress, and the ability to prevent nerve cell damage, as observed in herbal compounds and certain extracts.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) Neuroprotective effects are present in Dashmoola, which play a crucial role in alleviating the burdens of stress and anxiety, feelings that many face during difficult times, acting as an adaptogen, bolstering one’s ability to cope.[1] (2) The neuroprotective effects of Jatamansi provide calming benefits, reducing anxiety and stress, which are often linked to exacerbations of psoriasis, promoting overall well-being.[2] (3) This is a beneficial characteristic of certain substances, like those found in Saraswatarishta, which helps to protect nerve cells from damage or degeneration.[3] (4) This describes the potential of certain substances to protect the brain from damage, as seen in the context of certain herbal compounds.[4] (5) Estrogens have neuroprotective effects, reducing the risk of neurodegenerative diseases such as Alzheimer's and Parkinson's, according to the text.[5]
From: International Research Journal of Ayurveda and Yoga
(1) Effects that protect the nerves in the eye from damage.[6]
The concept of Neuroprotective effect in scientific sources
Neuroprotective effect describes a substance's capacity to safeguard nerve cells from harm or deterioration. This protection can be achieved through various mechanisms, including antioxidants, and is relevant in treating neurodegenerative diseases like Alzheimer's. It highlights the beneficial impacts on nerve cell health and survival.
From: International Journal of Pharmacology
(1) The text states that the neuroprotective effect of TSG is probably mediated by decreasing the expression of inflammation-associated and apoptosis-associated factors induced by MTI, and increasing the anti-inflammatory cytokine IL-10 production.[7] (2) Neuroprotective effect is a positive effect of some beta-lactam antibiotics, with ceftriaxone reducing neuronal mortality in experimental models of brain deprivation of oxygen and glucose.[8] (3) These are seen with vitexin against isoflurane-induced neurotoxicity by targeting the TRPV 1 and NR 2 B signaling pathways.[9]
From: Asian Journal of Pharmaceutics
(1) Statins have this effect by regulating cerebral perfusion and improving endothelial function.[10] (2) Preclinical studies have suggested that D-glucosamine may exert these through mechanisms such as antiinflammatory and antioxidant activity.[11] (3) These are beneficial actions that certain phytomedicines and nanocarriers may have against Huntington's disease.[12]
From: South African Family Practice
(1) The ability to protect nerve cells from damage, which alpha-lipoic acid possesses and may help with burning mouth syndrome.[13]
From: Journal of Medicinal Plants for Economic Development
(1) These are the effects of withaferin A that potentially offer benefits for conditions such as Alzheimer’s and Parkinson’s disease by protecting neurons from oxidative stress and inflammation.[14]
From: The Malaysian Journal of Medical Sciences
(1) Neuroprotective effects refer to the ability of kolaviron to prevent neuronal death, particularly when administered before exposure to cuprizone.[15] (2) This is the ability of a substance or treatment to protect nerve cells from damage, mentioned in the text.[16] (3) This refers to the effects of flavonoids on brain ischemia and neurodegenerative diseases.[17]
From: International Journal of Pharmacology
(1) Neuroprotective effect refers to the ability of a substance to protect nerve cells from damage, which nattokinase demonstrated against Aβ25-35 in PC12 cells.[18] (2) Neuroprotective effects refer to the ability of a substance, like gastrodin or GR, to protect nerve cells from damage and dysfunction.[19] (3) The ability of a substance or treatment to protect nerve cells from damage or death, particularly in the context of brain injury or disease.[20]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) A beneficial effect on nerve cells, observed for both ∆9-Tetrahydrocannabinol and Cannabidiol in a model of retinal neurotoxicity.[21] (2) Melatonin demonstrates a neuroprotective effect against hypoxia-induced retinal ganglion cell death in neonatal rats, safeguarding neural tissue.[22] (3) The neuroprotective effect of brain-derived neurotrophic factor is thought to result from its activation of the TrkB/MAPK/ERK 1/2/IP3K/Akt pathway, which actively inhibits processes like apoptosis and the damaging effects of glutamate.[23]