Significance of Naloxone
Naloxone is an opioid antagonist used in research to explore its mechanisms regarding antinociceptive effects related to opioid receptors. It acts as a pan-opioid receptor antagonist, enhancing inhibitory effects on acetylcholine-stimulated contractility in guinea pig ileum. Furthermore, studies have utilized Naloxone to examine its impact on the analgesic effects of Tragia plukenetii, revealing that it does not influence the plant's antinociceptive activity. Overall, Naloxone plays a significant role in understanding pain mechanisms.
Synonyms: Opioid antagonist
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The concept of Naloxone in scientific sources
Naloxone is an opioid receptor antagonist studied for its impact on the analgesic effects of Tragia plukenetii, demonstrating no effect on antinociceptive activity, and it enhances inhibitory effects on acetylcholine-stimulated guinea pig ileum contractility.
From: AYU (Journal of Research in Ayurveda)
(1) An opioid receptor antagonist used in the study to investigate its influence on the analgesic effects of Tragia plukenetii, which was found not to affect its antinociceptive activity.[1]
From: World Journal of Pharmaceutical Research
(1) A pan-opioid receptor antagonist that increases the inhibitory effects on acetylcholine-stimulated contractility of guinea pig ileum.[2]
From: Journal of Ayurveda and Integrative Medicine
(1) An opioid antagonist used in the study to investigate the mechanisms of AGG's antinociceptive effects, primarily with regard to opioid receptors.[3]