Significance of Myocardial necrosis
Myocardial necrosis, the death of heart muscle cells, is a critical condition. It can result from insufficient blood flow, causing biochemical and structural changes. This process is linked to various factors, including ischemia-reperfusion injury, specific medications, and toxic substances. Myocardial necrosis can be identified through elevated cardiac biomarkers and histopathological lesions, representing a severe finding often associated with ischemic heart diseases.
Synonyms: Myocardial infarction, Cardiac necrosis, Myocardial death, Cardiac muscle necrosis, Heart infarction
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Myocardial necrosis'
In Hinduism, myocardial necrosis signifies the death of heart muscle cells. This is determined through enzyme levels and evidence of cardiac damage.
From: International Research Journal of Ayurveda and Yoga
(1) Death of heart muscle cells, indicated by levels of enzymes and cardiac damage.[1]
The concept of Myocardial necrosis in scientific sources
Myocardial necrosis is the death of heart muscle tissue due to insufficient blood supply. It's linked to ischemic heart diseases, cytotoxic free radicals, and can occur in poisoning or following certain administrations, causing histopathological changes and elevated cardiac biomarkers.
From: International Journal of Pharmacology
(1) Necrosis that was present in IRI control rats but attenuated with diltiazem and bosentan treatment.[2] (2) Diabetic cardiomyopathy is caused by diabetic microvascular disease and myocardial metabolic disorders caused by this.[3] (3) ISO, HFD and HFD+ISO groups showed large area of red coloration, indicated these areas. It can be focally caused by Isoprenaline treatment.[4] (4) The present study demonstrated the cardioprotective effect of Bacopa monniera in ISP-induced model of this by improving endogenous antioxidant defense system.[5] (5) The rat model of ISO induced this serves as a model to evaluate cardiac dysfunctions.[6]
From: Asian Journal of Pharmaceutics
(1) The in vivo studies examined the effect of the drug on isoproterenol-induced condition.[7] (2) The death of heart muscle cells, quantified as a percentage of total myocardial volume after ischemia and reperfusion.[8]
From: The Malaysian Journal of Medical Sciences
(1) The death of heart muscle tissue, often indicated by raised serum cardiac biomarkers.[9]
From: Journal of Medicinal Plants for Economic Development
(1) The phrase describes the cell death in the heart muscle, which can be produced by cytotoxic free radicals, formed during a process.[10]
From: Onderstepoort Journal of Veterinary Research
(1) Significant histologic lesions were present in the heart of 12 sheep, characterized by multifocal to locally extensive areas of this.[11]
From: International Journal of Pharmacology
(1) This process, occurring in ischemia-reperfusion injured hearts, results in significant alterations in biochemical variables and lysosomal enzyme damage.[12] (2) The death of heart muscle cells resulting from insufficient blood flow and oxygen.[13]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) Exercise-induced protection against apoptosis and this involves MnSOD, calcium-handling proteins, and calpain.[14]