Significance of Multidrug resistance
Synonyms: Antimicrobial resistance, Drug resistance, Antibiotic resistance, Pharmacoresistance, Treatment resistance
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Multidrug resistance'
From: Journal of Ayurveda and Integrated Medical Sciences
(1) This is a complication in treating Typhoid fever, and has complicated treatment of infections, particularly with the emergence of resistance to multiple antibiotics.[1]
The concept of Multidrug resistance in scientific sources
From: International Journal of Pharmacology
(1) The development of this against β-lactam and other antibiotics has been reported.[2] (2) It is a critical barrier against the successful and complete removal of cancer cells in NSCLC.[3] (3) MRSA exhibits this, making it an important hospital and community pathogen.[4] (4) It is a phenomenon where bacteria become resistant to multiple drugs, making infections harder to treat.[5] (5) This is an inherent feature of many brain tumors and may have a role in disease progression or relapses.[6]
From: Asian Journal of Pharmaceutics
(1) The accumulation of different mechanisms of resistance leads to the development of multiple-resistant or even “pan-resistant” strains.[7] (2) It is a phenomenon where cells become resistant to multiple drugs.[8] (3) Future applications in cancer therapy include personalized medicine, combination therapies, and overcoming this.[9] (4) This is the ability of microorganisms to resist the effects of multiple antibiotics, complicating treatment options.[10] (5) A condition in tumour cells that is impacted by pH-sensitive quercetin and doxorubicin conjugated nanoparticles.[11]
From: The Malaysian Journal of Medical Sciences
(1) This is the ability of bacteria to resist multiple antibiotics, which poses a significant challenge in treating infections and is a major concern.[12] (2) This signifies the ability of microorganisms to resist multiple antimicrobial drugs, a significant characteristic of certain bacterial strains, particularly in the context of Acinetobacter baumannii infections.[13] (3) Multidrug resistance is developed by TA modules in pathogenic bacteria, creating problems during the treatments of disease.[14] (4) This is the ability of a bacterial strain to resist the effects of multiple antibiotics, and it can be associated with specific SCCmec types in CoNS isolates.[15] (5) A phenomenon where microorganisms develop resistance to multiple types of drugs, often linked to specific plasmids carrying resistance genes.[16]
From: Onderstepoort Journal of Veterinary Research
(1) This, abbreviated as MDR, facilitates the emergence and dissemination among STEC strains that are recovered from food animals.[17] (2) This is a condition where bacteria are resistant to multiple types of antibiotics, as observed in various strains like E. coli, P. aeruginosa, and Salmonella spp.[18] (3) Most examined E. coli isolates demonstrated high multidrug resistance levels against tetracycline and chloramphenicol (95.7% and 93.6%), respectively, followed by piperacillin, penicillin and streptomycin (90.4%, 88.3% and 88%), respectively.[19] (4) This is the resistance to multiple antibiotics, and the text indicates this is a growing concern for public health because it leads to prolonged illness and higher treatment failure rates.[20] (5) This is when Salmonella isolates show resistance to multiple antimicrobial agents, making infections harder to treat and highlighting a public health issue.[21]
From: Journal of Public Health in Africa
(1) Patients who had irregular treatment were exposed to this. This can be explained by the lack of systematic application of DOT (Directly Observed Treatment).[22] (2) This is a serious concern among non-fermenting gram-negative bacteria, making it essential to implement improved antibiotic stewardship and infection control measures.[23] (3) This refers to the resistance of bacteria to multiple antibiotics, and the text provides data on the prevalence of this resistance among various bacterial species.[24]
From: Journal of Medicinal Plants for Economic Development
(1) This is a phenomenon where microorganisms develop resistance to more than one class of antimicrobials, increasing infections.[25] (2) The ability of bacteria to resist the effects of multiple antibiotics, which poses a challenge to treatment and is a key aspect of the study's focus.[26] (3) This is the phenomenon where microorganisms develop resistance to multiple antimicrobial drugs, posing a significant challenge in treating infections and necessitating the development of new therapeutic strategies.[27]
From: South African Journal of HIV Medicine
(1) This is a condition in which the tuberculosis bacteria become resistant to multiple drugs, complicating treatment, and the strain was determined to be resistant to rifampicin.[28] (2) This is resistance to multiple antiretroviral drugs, and the development and transmission of this in resource-limited settings has the potential to undo the gains of national ART programs.[29] (3) Resistance to multiple drugs, and where this is identified by maternal virus genotyping prior to delivery, serious consideration may need to be given to LPV/r use as infant cARP.[30]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) This is the ability of microorganisms to withstand the effects of multiple antibiotics or antimicrobial agents.[31] (2) Multidrug resistance (MDR) is when bacterial isolates are non-susceptible to at least one agent in three or more antibiotic categories, according to the definition applied in this study.[32] (3) "Multidrug resistance" (MDR) is defined as resistance to three or more antimicrobial classes, and it is identified in some E. coli isolates in the study.[33] (4) This refers to the ability of bacteria to resist multiple drugs, making infections more difficult to treat and posing a greater threat to public health.[34] (5) Over 37% of the isolates showed multidrug resistance, which is a concerning finding due to the limited treatment options.[35]
From: Sustainability Journal (MDPI)
(1) This is a characteristic that evolves in organisms like Staphylococcus aureus, tracked through whole-genome sequencing to understand its development.[36] (2) Sublethal antibiotic treatment leads to this via radical-induced mutagenesis.[37]
From: International Journal of Pharmacology
(1) Multidrug resistance is a growing problem where pathogenic microorganisms develop resistance against commonly used commercial antimicrobial drugs due to indiscriminate use.[38] (2) Wu et al. explored the reversal effect of Carthami Flos on multidrug resistance in cancer cells in their 2013 research.[39] (3) Pathogenic microbes have developed multidrug resistance due to the indiscriminate use of antibiotics, particularly synthetic ones, leading to significant health issues, especially in developing countries.[40] (4) A phenomenon in cancer chemotherapy characterized by cross-resistance to various drugs, decreased intracellular drug concentration, and overexpression of membrane transport proteins like P-gp.[41] (5) Multidrug resistance is a significant barrier in cancer treatment, where cancer cells become resistant to multiple therapies, reducing the efficacy of treatments.[42]