Significance of Mucosal damage
Mucosal damage encompasses various injuries and alterations to the mucous membranes throughout the body. This can include harm to the gastrointestinal tract lining caused by irritants, radiation, or conditions like ulcerative colitis. Symptoms can also stem from the abnormal reflux of gastric contents, affecting the esophagus. Damage can result from factors like DNA damage, leading to inflammation and apoptosis. Protecting against and preventing this damage is crucial, with potential benefits from substances like Polybion and Emblica.
Synonyms: Mucosal injury, Mucosal lesion
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Mucosal damage in scientific sources
Mucosal damage involves injury or disruption of the mucosal lining, causing dysfunction and inflammation. It can occur in various areas, including the colon, nasal passages, and gastrointestinal tract. This damage may be caused by conditions, treatments, and irritants.
From: International Journal of Pharmacology
(1) Any injury or alteration to the gastric lining, which could affect substance absorption.[1] (2) Mucosal damage in the colon can be attenuated by Astragaloside IV, as evidenced by reductions in histological damage scores and MPO activity.[2] (3) Rutin can be beneficial for preventing mucosal damage in patients undergoing cisplatin treatment.[3]
From: South African Family Practice
(1) This affects the sensitivity of tests, and the titres of antiendomysial antibodies and anti-tTG correlate with the degree of this, and it is an important factor in the diagnosis of the condition.[4] (2) The symptoms and of gastro-oesophageal reflux disease are produced by the abnormal reflux of gastric contents into the oesophagus, as described in the article.[5]
From: The Malaysian Journal of Medical Sciences
(1) This is a result of DNA damage, release of reactive oxygen species, and the activation of transcription factors, including nuclear factor-kB, which can lead to the production of proinflammatory cytokines and apoptosis.[6]
From: Onderstepoort Journal of Veterinary Research
(1) This refers to lacerations and scars observed in the fundus, indicating the presence of previous active ulcerous or traumatic lesions in the stomach.[7]