Significance of Mucoadhesive tablet
Mucoadhesive tablets are specialized solid dosage forms engineered to adhere to mucosal surfaces, such as those in the gastrointestinal tract and buccal area. These tablets facilitate controlled and prolonged release of medications, improving drug absorption and retention. For instance, mucoadhesive tablets can be used to deliver drugs like omeprazole and Levosalbutamol sulphate, enhancing therapeutic efficacy by prolonging the gastric residence time and optimizing the overall delivery of the active pharmaceutical ingredient.
Synonyms: Bioadhesive tablet, Mucoadhesive formulation, Mucoadhesive dosage form
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The concept of Mucoadhesive tablet in scientific sources
Mucoadhesive tablets are specialized formulations designed to stick to mucosal surfaces, facilitating controlled and prolonged drug release, as demonstrated with medications like omeprazole and Levosalbutamol sulphate, ultimately enhancing drug absorption and effectiveness.
From: Asian Journal of Pharmaceutics
(1) This is a trilayered tablet of itraconazole with zero-order release.[1] (2) Some researchers had prepared and reported new amoxicillin formulations such as float tablets, these, and pH-sensitive excipients composition microspheres, which were able to reside in the gastrointestinal tract for an extended period for a more effective H. pylori eradication.[2] (3) These are tablets of atenolol using response surface methodology.[3] (4) These tablets are used for carbamazepine sublingual administration and undergo preformulation studies to optimize their properties.[4] (5) Tablets containing Chlorhexidine MCM-41 that are designed for topical use, according to the text.[5]