Significance of Minimum inhibitory concentration
Minimum inhibitory concentration (MIC) consistently refers to the lowest concentration of a substance, such as an extract, compound, or antimicrobial agent, needed to prevent the visible growth of a microorganism. This measurement is used to assess the effectiveness of a substance against bacteria, fungi, or other microbes. Lower MIC values generally indicate a more potent antimicrobial effect, with the determination often involving specific assays and methods like broth dilution.
Synonyms: Mic, Lowest concentration, Inhibitory concentration, Minimal inhibitory concentration
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Minimum inhibitory concentration'
In Hinduism, Minimum Inhibitory Concentration (MIC) represents the lowest amount of a substance, like plant extracts or essential oils, needed to halt the growth of harmful microorganisms. This value, determined through various methods, indicates the substance's effectiveness as an antimicrobial agent.
From: Journal of Ayurvedic and Herbal Medicine
(1) This refers to the lowest concentration of the plant extracts that was required to inhibit the growth of the bacteria, determined using the micro broth dilution method.[1] (2) This is the lowest concentration of a substance that inhibits the growth of a microorganism, and it was assessed to determine the antibacterial property of aqueous and ethanolic extracts of Aloe vera gel against Enterococcus faecalis.[2] (3) These are the lowest concentrations of a substance needed to prevent the growth of microorganisms, determined using the agar well diffusion method.[3] (4) The lowest amount of a drug needed to prevent the visible growth of a microorganism after a period of incubation, which was assessed for the pomegranate extract.[4]
From: Journal of Ayurveda and Integrated Medical Sciences
(1) The Minimum Inhibitory Concentration (MIC) was determined to assess the lowest concentration of the methanol extract that prevented visible growth, as part of the study.[5] (2) This term is defined as the lowest amount of a compound required to stop the growth of microorganisms, as used in the study.[6] (3) This is the lowest concentration of a substance needed to inhibit the growth of a microorganism, with lower values indicating a more effective antimicrobial agent.[7]
From: International Research Journal of Ayurveda and Yoga
(1) In a study, the essential oil isolated from P. corylifolia was evaluated against fungus Microsporum canis, Trichophyton rubrum, and Trichophyton mentagrophytes and the minimum inhibitory concentration was observed.[8]
The concept of Minimum inhibitory concentration in scientific sources
Minimum Inhibitory Concentration (MIC) is the lowest concentration of an antimicrobial agent, extract, or substance that prevents visible growth of a microorganism. It is crucial for determining antimicrobial potency and effectiveness, often measured in µg/ml and used to assess drug susceptibility.
From: International Journal of Pharmacology
(1) These are the lowest concentrations of a substance, such as a plant extract, required to inhibit the growth of a microorganism, like vancomycin-resistant S. aureus.[9] (2) These values of crude extract and purified compounds were determined by NCCLS microbroth dilution methods.[10] (3) Also known as MIC, this is the extract concentration at which the bacteria show no visible growth, determined by the broth microdilution method.[11] (4) This concentration (MIC) was calculated by plotting the natural logarithm of the concentration of extract against the square of zones of inhibition.[12] (5) For calculation of this concentration, or MIC, which represents the concentration that completely inhibits the growth of microorganisms, a micro-dilution broth susceptibility assay was used.[13]
From: Asian Journal of Pharmaceutics
(1) Mupirocin exerts a bacteriostatic effect at this concentration, with bactericidal concentrations being greater than the MIC.[14] (2) The minimum concentration of antibiotic that may be effective if successful local delivery were achieved.[15] (3) The lowest concentration of an antibiotic that inhibits the growth of a microorganism.[16] (4) This is the lowest concentration of an antimicrobial that will inhibit the visible growth of a microorganism after overnight incubation.[17] (5) This is a measurement of the smallest amount of a substance needed to stop the growth of a microorganism.[18]
From: Journal of Medicinal Plants for Economic Development
(1) The minimum inhibitory concentration (MIC) is the lowest concentration of a substance that inhibits the growth of a microorganism, and the study determines the MIC of Clausena anisata oils against M. tuberculosis.[19] (2) The minimum inhibitory concentration is a measure of the lowest concentration of a substance needed to inhibit the growth of a bacterium, indicating its antibacterial potency.[20] (3) The minimum inhibitory concentration (MIC) is the lowest concentration of a substance that prevents visible growth of a specific microorganism after an overnight incubation period.[21] (4) This is the lowest concentration of a substance that is needed to prevent the growth of a microorganism, used to determine its effectiveness.[22] (5) This is a laboratory measurement used to determine the lowest concentration of an antimicrobial agent needed to stop the growth of a specific microorganism.[23]
From: The Malaysian Journal of Medical Sciences
(1) The treated cultures were then incubated at 37 °C for the required incubation time at this value.[24] (2) This is the MIC of bacteria-resistant organisms that the current dose used in the ICU is not guided by.[25] (3) Leaves from Terminalia catappa extracted with petroleum ether, chloroform or ethyl acetate also inhibit agar growth of foodborne Escherichia coli, yielding these values.[26] (4) The lowest concentration of a substance that is required to prevent the growth of a specific microorganism, used to determine effectiveness.[27] (5) Minimum inhibitory concentrations (MICs) and plant flavonoids as antibacterials are used to combat MDR bacteria, indicating that natural plant products can be a useful source.[28]
From: Onderstepoort Journal of Veterinary Research
(1) These are the lowest concentrations of antimicrobial drugs that effectively inhibit bacterial cell division, and the method is used to determine the susceptibility of bacteria to various antimicrobial drugs, which yields repeatable results.[29] (2) This phrase refers to a specific measurement in scientific studies, often used in the context of testing antibiotics and their effects.[30] (3) The lowest concentration of an antibiotic that prevents the growth of a bacterium, recognized as a method to assist in determining the correct antibiotic dosage for animals.[31]
From: Journal of Public Health in Africa
(1) Most isolates had this of 1 µg/mℓ for colistin.[32] (2) This is the lowest concentration of an antifungal drug that inhibits the growth of a fungus, and it is a measure of drug resistance.[33]
From: South African Family Practice
(1) This is the lowest concentration of an antimicrobial agent that is required to inhibit the growth of a specific microorganism, which is critical for determining effective treatment.[34]
From: South African Journal of HIV Medicine
(1) Minimum inhibitory concentrations, or MICs, are laboratory measurements that indicate the lowest concentration of an antifungal drug needed to inhibit the growth of the fungus.[35]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) Minimum inhibitory concentration (MIC) is the lowest concentration of an antibiotic that inhibits the growth of a microorganism, and it is relevant to gentamicin effectiveness.[36] (2) Several methods have been proposed as suitable for the determination of MICs, such as the E-test, broth and agar dilution, and disk di ff usion methods, in vivo and in vitro.[37] (3) The minimum inhibitory concentration (MIC) of each antibiotic was determined using gradient strips, indicating the lowest concentration needed to inhibit visible growth of Campylobacter isolates.[38] (4) Minimum inhibitory concentrations (MICs) of AgNSs and AgNPs were determined against reference strains and multidrug-resistant isolates to assess their ability to inhibit bacterial growth.[39] (5) Minimum inhibitory concentration, or MIC, of penicillin was evaluated firstly at 0.5, 1.0, and 2.0 mg · L − 1 , and 1% ( v / v ) B. pumilus culture solution were inoculated in the LB medium.[40]
From: Sustainability Journal (MDPI)
(1) Minimum inhibitory concentrations required to inhibit growth in 50% of the isolates (MIC 50 ) were calculated for each antibiotic using median resistance values.[41] (2) The minimum inhibitory concentration of the oil against A. niger ranges from 0.016 to 0.4 percent volume by volume, indicating the concentration required to inhibit fungal growth.[42]
From: International Journal of Pharmacology
(1) Minimum inhibitory concentration is the lowest concentration of an antimicrobial substance that prevents the visible growth of a microorganism.[43] (2) The Minimum inhibitory concentration method is employed to determine the lowest concentration of a substance, like zerumbone, that prevents the visible growth of bacteria or fungi.[44] (3) The Minimum Inhibitory Concentration (MIC) denotes the lowest concentration of an antimicrobial substance that visibly inhibits bacterial growth.[45] (4) The Minimum Inhibitory Concentration (MIC) is the lowest concentration of an antimicrobial agent, such as clove aqueous extract, that prevents the visible growth of a microorganism.[46] (5) Minimum Inhibitory Concentration (MIC) is defined as the lowest concentration of a Pangi seed extract that causes a 90% reduction in bacterial growth within 24 hours.[47]