Significance of MicroRNA
MicroRNA refers to small noncoding RNA molecules that are crucial for regulating gene expression by silencing target mRNAs. These molecules have specific functions in various tissues, including renal tissues, and are of particular interest in colorectal cancer research as potential diagnostic biomarkers and therapeutic targets. MicroRNAs also interact with epigenetic mechanisms to influence phenotypic traits and are involved in essential cellular processes, including apoptosis and signaling, highlighting their importance in cancer progression.
Synonyms: Mirna, Non-coding rna
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The concept of MicroRNA in scientific sources
MicroRNA (miRNA) consists of short noncoding RNA molecules that critically regulate gene expression by silencing target mRNAs. They are essential in various cellular processes, including cancer progression and specific functions in renal tissues.
From: The Malaysian Journal of Medical Sciences
(1) These are small non-coding RNA molecules of 18-24 nucleotides, emerging as key regulators of post-transcriptional processes in various biological systems.[1] (2) These are also related to epigenetics, and are mentioned in the context of hypertension, representing a subject of study.[2] (3) MicroRNA are small non-coding RNA molecules that regulate protein-coding gene expression.[3] (4) These and ROS have potential roles in colorectal cancer as diagnostic biomarkers and therapeutic targets, as indicated by the text.[4] (5) Small non-coding RNAs that play a role in regulating gene expression and can be involved in apoptosis and cellular signaling mechanisms.[5]