Significance of Marker enzyme
Marker enzymes are specific enzymes that serve as vital indicators of various health conditions, particularly liver damage. Key examples include ALT, AST, ALP, and LDH, which are assessed through serum levels to evaluate liver integrity. These enzymes not only reflect liver and kidney functions but also indicate tissue health and the presence of diseases, making them essential for diagnosing and monitoring organ status. Their measurement is crucial in various studies related to organ health and damage evaluation.
Synonyms: Biomarker
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The concept of Marker enzyme in scientific sources
The keyphrase "Marker enzyme" refers to enzymes like catalase that indicate health status in organisms like silkworms and are used to assess tissue function and the effects of treatments, such as Doxorubicin, via amniotic fluid monitoring.
From: World Journal of Pharmaceutical Research
(1) An enzyme, such as Lactate Dehydrogenase, used as an indicator for cellular health and specific diseases.[1] (2) Enzymes such as CK-MB, LDH, AST, and ALT, which indicate myocardial damage when released into serum.[2] (3) Enzymes like SGOT and SGPT that serve as indicators of liver health and function, crucial for evaluating the hepatoprotective activity.[3] (4) Biochemical indicators that provide information on the health status of organs; used in the study to evaluate the effects of Yoyo cleanser bitters.[4] (5) Specific enzymes whose levels in serum indicate liver injury or damage, such as AST, ALT, and ALP.[5]
From: Ancient Science of Life
(1) Specific enzymes that serve as indicators of the presence of certain conditions, such as cancer, including lactate dehydrogenase and alkaline phosphatase.[6] (2) Enzymes such as alkaline phosphatase (ALP), acid phosphatase (ACP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and lactate dehydrogenase (LDH) that are measured to assess liver and kidney function.[7] (3) Enzymes such as alanine aminotransferase and aspartate aminotransferase, which are elevated in serum during liver damage.[8] (4) Enzymes like ACP, ALP, AST, and ALT used to assess the integrity of liver and kidney functions in serum, urine, and tissue samples.[9] (5) Specific enzymes that are released into blood circulation and urine, indicative of tissue damage or pathological conditions in the kidneys, such as AST, ALT, ACP, and ALP.[10]
From: Journal of Ayurveda and Integrative Medicine
(1) Biochemical indicators used to diagnose liver damage; their levels in plasma reflect cellular integrity and liver health.[11]