Significance of Liquid chromatography-tandem mass spectrometry

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is an advanced analytical technique that combines liquid chromatography with mass spectrometry for the separation, identification, and quantification of compounds. It is characterized by its sensitivity and specificity, making it valuable in various applications, such as drug analysis and examining biological samples like human blood and rabbit plasma. This sophisticated technique is widely used in both preclinical and clinical laboratories for analyzing low molecular weight molecules and detecting substances in complex mixtures.

Synonyms: Lc-ms/ms, Tandem mass spectrometry

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The concept of Liquid chromatography-tandem mass spectrometry in scientific sources

Science Books

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a sophisticated analytical technique crucial for detecting and quantifying compounds in complex mixtures, including herbal medicines, and is particularly sensitive for measuring sirolimus in human blood samples.

Significance in Scientific journals, articles, etc.:

From: World Journal of Pharmaceutical Research

(1) A technique used for rapid analysis of substances in human plasma.[1] (2) An advanced analytical method integrating liquid chromatography and mass spectrometry for the detection of substances, particularly for forensic applications outlined in the text.[2] (3) An analytical technique used to identify and quantify compounds based on their mass-to-charge ratio.[3] (4) An analytical technique combining liquid chromatography with mass spectrometry for separating and analyzing compounds.[4] (5) A sophisticated analytical technique used for the sensitive determination of drug compounds in various biological samples.[5]

From: Ancient Science of Life

(1) A modern analytical technique used to identify toxic constituents transferred into media during the Shodhana process.[6]

From: AYU (Journal of Research in Ayurveda)

(1) A sophisticated analytical technique (LC-MS/MS) used for detecting and quantifying compounds in complex mixtures, including herbal medicines.[7]

This section includes scientific research in the field of healthcare, often involving traditional medicine systems such as Ayurveda, Unani, Siddha and Holistic health. It includes papers from scientific journals classified as either original, clinical or experimental research, review articles or case reports.