Significance of Lipid peroxidation
Lipid peroxidation refers to the oxidative degradation of lipids, a process that can cause significant cellular damage. It occurs when free radicals attack lipids in cell membranes, leading to various health issues including cognitive dysfunction, diabetes, and aging. This degradation is often measured by the production of malondialdehyde (MDA), a biomarker for oxidative stress. The implications of lipid peroxidation are significant in multiple diseases, highlighting the importance of understanding this process in both biological systems and potential therapeutic approaches.
Synonyms: Lipid oxidation
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The concept of Lipid peroxidation in scientific sources
Lipid peroxidation involves the oxidative degradation of lipids, damaging cell membranes and linking to liver toxicity, chronic diseases, and negatively affecting the quality of medicinal oils through oxidation and off-flavors.
From: World Journal of Pharmaceutical Research
(1) The oxidative degradation of lipids, associated with cellular damage in diabetes, which may be prevented by antioxidants.[1] (2) A process in which free radicals steal electrons from the lipids in cell membranes, resulting in cell damage and is often marked by the rise of products like MDA.[2] (3) A process where free radicals cause damage to cell membrane lipids, which can be inhibited by antioxidants.[3] (4) A process in which free radicals attack lipids, leading to cell membrane damage, relevant in assessing neuronal health in the context of oxidative stress.[4] (5) A process in which free radicals attack lipids in biological membranes, often exacerbated by cadmium exposure, leading to cell damage.[5]
From: Ancient Science of Life
(1) A process involving the oxidative degradation of lipids, which can damage cellular membranes and is influenced by substances like CCl 4.[6] (2) Lipid peroxidation is a process in which free radicals attack lipids in cell membranes, leading to cell damage and the production of reactive lipid radicals.[7] (3) A process in which free radicals attack lipids in cell membranes, leading to cellular damage, which is measured in studies of liver and brain tissues.[8] (4) A process where free radicals attack double bonds in polyunsaturated lipids, leading to irreversible loss of fluidity and structural integrity of the cell membrane.[9] (5) The oxidative degradation of lipids, which can lead to cellular damage and is often increased in conditions of oxidative stress.[10]
From: Journal of Ayurveda and Integrative Medicine
(1) Lipid peroxidation is a process measured in the study to evaluate oxidative damage, specifically by assessing levels of malondialdehyde (MDA) in cell lysates.[11] (2) The oxidative degradation of lipids, which was found to be increased by CCl4 administration but reduced by D. hamiltonii treatment.[12] (3) A process being measured in the study to evaluate oxidative stress levels caused by C.M extract in rats.[13] (4) The oxidative degradation of lipids, characterized by increased levels in response to aluminum toxicity in Drosophila.[14] (5) The oxidative degradation of lipids, resulting in cell membrane damage, often measured as a biomarker for oxidative stress.[15]
From: AYU (Journal of Research in Ayurveda)
(1) A process involving the oxidative degradation of lipids, which is commonly evaluated in studies of hyperlipidemia and related treatments.[16] (2) The oxidative degradation of lipids that can result in cell damage, frequently associated with various diseases.[17] (3) A process indicating oxidative stress within tissues, which was monitored in relation to the treatment effects.[18] (4) A process that occurs when free radicals attack lipids in cell membranes, measured in the study to assess oxidative damage in brain tissue.[19] (5) A process in which free radicals cause oxidative damage to lipids, leading to cell injury and is often measured in relation to diabetes.[20]
From: The Malaysian Journal of Medical Sciences
(1) A process in which free radicals damage lipids, contributing to skin aging and diseases.[21] (2) The oxidative degradation of lipids, which can lead to cell damage and is increased in diabetic patients.[22] (3) The oxidative degradation of lipids, leading to cell membrane damage and increased fragility.[23] (4) Lipid peroxidation refers to the oxidative degradation of lipids, leading to cell damage and formation of toxic by-products such as malondialdehyde (MDA).[24] (5) Lipid peroxidation is the oxidative degradation of lipids, resulting in cell damage and serving as an indicator of oxidative stress.[25]
From: International Ayurvedic Medical Journal
(1) The oxidative degradation of lipids, typically leading to cell damage and is a target for antioxidant activity.[26] (2) An oxidative damage process affecting cellular membranes that was measured in the study to evaluate lung tissue health.[27] (3) A process leading to cellular damage caused by oxidative degradation of lipids, observed in NMU control rats, but decreased in rats treated with Kanchanara Guggulu.[28] (4) Lipid peroxidation is a process where free radicals attack lipids in cell membranes, leading to cell injury and is measured to assess antioxidant effects.[29] (5) The oxidative degradation of lipids, often resulting from oxidative stress, leading to cell damage.[30]
From: Journal of Indian Society of Periodontology
(1) A damaging process often initiated by arecoline that can lead to various oral pathologies including OSMF.[31] (2) A process in which free radicals attack lipids, leading to cell membrane damage and contributing to tissue damage.[32] (3) The oxidative degradation of lipids, which leads to cell membrane damage and is used as a biomarker for oxidative stress.[33]
From: Journal of Ayurveda and Holistic Medicine
(1) The oxidative degradation of lipids leading to cell membrane damage, often assessed in liver toxicity studies.[34] (2) A detrimental process wherein fats are oxidized, resulting in off-flavors and reduced quality of medicinal oils.[35]