Significance of Limit of quantification
The limit of quantification (LOQ) is defined as the lowest concentration of an analyte that can be quantitatively measured with acceptable precision and accuracy. This definition encompasses several specific contexts, including the minimum detectable concentrations for various substances, such as fosinopril sodium, Doxycycline Hyclate, and valsartan. The LOQ is essential in analytical methods, as it ensures reliable quantification of substances in different samples, allowing for effective measurement and evaluation of drugs and compounds.
Synonyms: Loq, Detection limit, Analytical sensitivity, Measurement limit
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Limit of quantification in scientific sources
The Limit of Quantification (LOQ) is the minimal concentration of a substance that can be accurately and precisely detected and reliably quantified in analytical measurements, ensuring data integrity in various applications.
From: International Journal of Pharmacology
(1) The lowest concentration of enhydrin and uvedalin that can be quantified, determined to be 7.825 and 96.5 μg mL –1, respectively.[1] (2) It is the minimum concentration that could be measured with CV<10%.[2] (3) Limit of Detection and this were established at a signal to noise ratio (S/N) of 3.3 and 10.[3]
From: Asian Journal of Pharmaceutics
(1) These values are given in Table 5 and is a part of the validation.[4] (2) The LOQ was found to be 0.0852 μg/mL, it is the lowest concentration of analyte that can be quantitatively determined.[5] (3) A measurement that was taken during the experiment using the novel bienzymatic assay method.[6]
From: Sustainability Journal (MDPI)
(1) The limit of quantification (LoQ) was reported based on the lowest concentration that could be measured with an acceptable relative standard deviation.[7] (2) The limit of quantification (LOQ) represents the lowest concentration of procymidone that can be reliably measured by the analytical method.[8] (3) Values reported as 'blq' indicate that the concentration of the specific metal or contaminant in the sample was below the limit of quantification for the analytical method employed.[9]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) The limit of quantification (LOQ) is the lowest concentration of a pesticide, such as pirimiphos-methyl or deltamethrin, that can be reliably measured in stored rice with acceptable precision and accuracy.[10] (2) The limit of quantification is the concentration level defined by a signal-to-noise ratio of 10, representing the lowest amount of a target compound that can be reliably and quantitatively measured in the various wheat sample matrices.[11] (3) The limit of quantification (LOQ) is a crucial parameter in risk assessment, representing the lowest amount of a substance that can be reliably measured in a sample.[12]
From: International Journal of Pharmacology
(1) The limit of quantification for the HPLC method used to analyze nitrofurazone was determined to be 20 ng mL -1.[13] (2) The calculated limit of quantification for warfarin in human plasma was 200 ng/mL.[14]