Significance of LDH
LDH, or lactate dehydrogenase, is an enzyme that serves several important functions in medical evaluations. It is primarily analyzed in blood tests to assess myocardial infarction and indicates tissue damage when elevated, which can occur in conditions such as muscular dystrophy and various cancers, including multiple myeloma. Additionally, LDH is crucial in energy production and plays a role in the metabolic interactions between tumor cells and cancer-associated fibroblasts. Elevated LDH levels can signal significant health concerns.
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The concept of LDH in scientific sources
LDH, or Lactate Dehydrogenase, is an enzyme that serves as a vital cardiac marker, indicating tissue damage. Its levels in the blood can provide crucial insights into heart health and injury assessment.
From: The Malaysian Journal of Medical Sciences
(1) These were measured to evaluate heart health by detecting specific proteins released into the bloodstream when the heart muscle is damaged or stressed, serving as indicators of cardiac function.[1] (2) Lactate dehydrogenase, an enzyme found in many tissues, including the liver, and can be measured in the blood to assess cell damage.[2] (3) Lactate dehydrogenase, an enzyme that can be elevated in certain cancers, including multiple myeloma, and it can be used to assess the risk of myeloma.[3] (4) These are lactate dehydrogenases that catalyse the interchange of lactate and pyruvate and play a role in the metabolic interplay between tumour cells and CAFs.[4]