Significance of Isocratic elution

Isocratic elution is a chromatographic technique where the mobile phase composition remains constant throughout the separation process. This method utilizes a single solvent or a mixture of solvents consistently during the analysis. It is particularly valued for its simplicity and reproducibility, making it useful in various applications, such as the determination of compounds like Neostigmine. Overall, isocratic elution is essential for achieving reliable separation results in high-performance liquid chromatography (HPLC) and other chromatography methods.

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The concept of Isocratic elution in scientific sources