Significance of Interleukin -8
Interleukin-8 (IL-8) is a pro-inflammatory cytokine that serves as a potent chemotactic factor for neutrophils and is quantitatively assessed in serum samples. It plays a crucial role in the inflammatory response by attracting and activating neutrophils, particularly in conditions like chronic periodontitis and infections from bacteria such as Helicobacter pylori. IL-8 is also involved in intestinal responses influenced by Bacteroides fragilis enterotoxin and is elevated in various inflammatory conditions, including varicose veins.
Synonyms: Cytokine, Inflammatory mediator, Il-8, Inflammatory cytokine
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The concept of Interleukin -8 in scientific sources
Interleukin-8 is a proinflammatory cytokine crucial in inflammatory responses, influencing skin health and aging by attracting and activating neutrophils and other immune cells, thereby playing a significant role in immune regulation.
(1) Interleukin-8 is a proinflammatory cytokine, and it can be analyzed to predict and monitor intra-amniotic inflammation in pPROM.[1] (2) This is a type of cytokine that can be secreted by mast cells, and the activity of these cells against tumours is regulated by this particular substance, as mentioned.[2] (3) This is a substance whose intestinal epithelial cell secretion is induced by Bacteroides fragilis enterotoxin through various pathways, as stated in the text.[3] (4) A molecule delivered by macrophages that plays a role in inflammation following nerve injury.[4]