Significance of Insulin resistance
Insulin resistance is a condition where the body's cells don't respond effectively to insulin, leading to elevated blood sugar. It's linked to type 2 diabetes, PCOS, obesity, metabolic syndrome, and cardiovascular diseases. Factors like genetics, lifestyle, diet, and certain environmental exposures contribute. It can be improved through diet, exercise, and certain treatments, and is a key focus across various fields of study.
Synonyms: Glucose intolerance, Metabolic syndrome, Prediabetes, Hyperinsulinemia
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
Hindu concept of 'Insulin resistance'
Hinduism is not mentioned in the text. Insulin resistance, as described in the text, is a condition where cells don't respond to insulin, leading to high blood sugar, type 2 diabetes, PCOS, and other metabolic issues, often linked to obesity and lifestyle.
From: Journal of Ayurveda and Integrated Medical Sciences
(1) Lipotoxicity, which is a metabolic dysfunction associated with altered lipid homeostasis, is considered as one of the cause behind insulin resistance as well as pancreatic B cells dysfunction.[1] (2) Insulin resistance occurs when the body's cells become less responsive to insulin, resulting in the accumulation of carbohydrates in the bloodstream, primarily in the form of glucose.[2] (3) A proper Yoga program after medical opinion can improve accumulated fat and insulin resistance which is associated with PCOD.[3] (4) An endocrine dysfunction that causes acanthosis nigricans, dyslipidemia, Acne, Alopecia and metabolic syndrome, cardiovascular disease, obstructive sleep apnoea, obesity etc.[4] (5) A metabolic condition often associated with PCOS, where the body's cells do not respond effectively to insulin, leading to higher blood sugar levels.[5]
From: International Research Journal of Ayurveda and Yoga
(1) A condition where tissues become insensitive to insulin, leading the pancreas to secrete excessive insulin in an attempt to maintain normal blood glucose levels.[6] (2) Acanthosis Nigricans is another sign that is manifested due to this condition.[7] (3) Obese individuals have increased amounts of non-esterified fatty acids, glycerol, hormones, cytokines, pro-inflammatory markers, and other substances involved in the development of insulin resistance.[8] (4) Fasting promotes blood sugar control by reducing this.[9] (5) A condition frequently associated with PCOS and Obesity that can interfere with implantation and development of embryo.[10]
From: Journal of Ayurvedic and Herbal Medicine
(1) Insulin resistance is considered an important cause of Non-Insulin Dependent Diabetes Mellitus, where body cells fail to utilize insulin properly, contributing to the condition.[11] (2) This is a condition in which the body's cells do not respond properly to insulin, which can lead to high blood sugar levels.[12] (3) This is the major pathogenesis of diabetes mellitus where there is little or no biological effect of tissues or cells for insulin, and this condition can cause more complicated consequences like cardiovascular disease.[13] (4) Type 2 diabetes mellitus is caused by insulin resistance in target cells which is more prevalent than type 1, as indicated in the provided text.[14] (5) A condition that may be contributed to by the alteration of metals status, potentially leading to diabetic complications.[15]
The concept of Insulin resistance in scientific sources
Insulin resistance is a condition where cells don't respond effectively to insulin, leading to elevated blood sugar. It's linked to type 2 diabetes, PCOS, obesity, cardiovascular risk, and metabolic abnormalities.
From: International Journal of Pharmacology
(1) Insulin resistance is a condition in which cells do not respond effectively to insulin, leading to elevated blood sugar levels, and the study explores sildenafil's impact on it.[16] (2) A condition in which cells do not respond normally to insulin, leading to increased blood sugar and is considered a risk factor for glucose intolerance.[17] (3) Yacon syrup is an excellent source of FOS and its long-term ingestion produced beneficial health effects on obese women with it.[18] (4) In aged rats, ursolic acid decreased proinflammatory cytokines IL-6 and IL-1â levels to ameliorate adipose tissue this.[19] (5) A condition exerted by over expression of phosphoenolpyruvate carboxykinase, potentially solvable by using D-glutamic acid.[20]
From: Journal of Metabolic Health
(1) The journal, previously identified as Journal of Insulin Resistance, published the original article, indicating the field of study related to the research.[21] (2) Insulin resistance is defined in the text, and although the two conditions are fundamentally intertwined, they are intrinsically different conditions, and the hyperglycaemic–euglycaemic clamp test is considered to be the ‘gold-standard’ test for it.[22] (3) This is a condition where the body's cells do not respond effectively to insulin, and the study measured this using HOMA-IR.[23] (4) This phrase is mentioned in the context of keywords, indicating a potential relationship between insulin and other conditions. It does not have a specific definition provided within the text, but it is related to the context of hyperinsulinemia and Polycystic Ovary Syndrome.[24] (5) This is a state where cells become less responsive to insulin, which can progress to a point where the beta-cells cannot control blood glucose.[25]
From: The Malaysian Journal of Medical Sciences
(1) "Insulin resistance" is a condition in which cells do not respond properly to insulin, leading to elevated blood sugar levels, and it is linked to oxidative stress, dyslipidemia, and type 2 diabetes mellitus.[26] (2) Hepatic p53 level was increased in type II diabetic patients and positively related to this.[27] (3) This study showed the association with acute coronary syndrome in the young Japanese population.[28] (4) This is a condition in which the body's cells do not respond effectively to insulin, a hormone that regulates blood sugar, which is a factor in the development of gestational diabetes during pregnancy.[29] (5) It is a factor in the development of type 2 diabetes, and it is combined with defective secretion of insulin by pancreatic β-cells.[30]
From: Asian Journal of Pharmaceutics
(1) The homeostasis model assessment of insulin resistance (HOMA-IR) was used in the study.[31] (2) A condition in which cells do not respond effectively to insulin.[32] (3) A condition associated with type II diabetes where cells do not respond to insulin.[33] (4) This is a condition where cells do not respond effectively to insulin, leading to elevated blood glucose levels.[34] (5) It is mentioned in regulation and reduction of blood sugar and insulin resistance.[35]
From: South African Family Practice
(1) Low-dose OCs may cause this.[36] (2) This is an endocrine/metabolic medical complication that is associated with obesity.[37] (3) A condition where the body's cells do not respond effectively to insulin, often linked to type 2 diabetes and sometimes hypertension, requiring careful management strategies.[38] (4) This is a condition where the body's cells do not respond properly to insulin, which is not a major factor in type 1 diabetes.[39] (5) This is a condition wherein cells do not respond effectively to insulin, which can contribute to elevated blood sugar levels.[40]
From: African Journal of Primary Health Care and Family Medicine
(1) This is a condition in which the body's cells do not respond properly to insulin, potentially leading to diabetes.[41] (2) This is when the body's cells don't respond properly to insulin, and the study noted that fructose-sweetened beverages may promote this condition.[42] (3) This is a condition to which anthropometric factors are more strongly related, and individuals are more prone to it when the factors are higher.[43] (4) This is a condition in which the body's cells do not respond properly to insulin, leading to elevated blood glucose levels and increasing the risk of type 2 diabetes.[44] (5) This is a condition that was common among people living with diabetes, and negative attitudes towards insulin may have been fuelled by family or community misconceptions about insulin.[45]
From: South African Journal of HIV Medicine
(1) The study notes that a problem in the body's ability to use insulin is a key factor in the development of a liver condition in people with HIV.[46] (2) This can develop in some instances of HIV-infected patients, resulting from the inflammatory changes and the metabolic toxicities.[47] (3) This refers to a condition where the body's cells do not respond properly to insulin, which can be associated with visceral fat accumulation.[48] (4) This condition occurs when cells do not respond normally to insulin, a hormone that regulates blood sugar, potentially leading to elevated blood sugar levels and other health issues.[49] (5) Insulin resistance, measured by log homeostatic model assessment (HOMA), was a component of metabolic syndrome, and it was associated with arterial stiffness in the study.[50]
From: Journal of Public Health in Africa
(1) Insulin Resistance refers to the effect of broccoli sprouts on insulin resistance in type 2 diabetic patients.[51] (2) The text uses this term to refer to a condition where the body's cells do not respond effectively to insulin, and its link to other health issues is mentioned.[52] (3) Insulin resistance can be prevented by TNF-α, and for this reason, TNF-α is one of the appropriate molecular factors to prevent inflammation.[53] (4) Insulin resistance is a condition in which the body cannot release insulin, and it is a cause of type 2 diabetes.[54] (5) This is a condition where cells do not respond properly to insulin, which is a key factor in type II diabetes, and the study looked at this.[55]
From: South African Journal of Physiotherapy
(1) This is one of the most common HAART-related metabolic complications that is associated with the use of Highly Active Antiretroviral Therapy.[56] (2) This is a characteristic of type 2 diabetes mellitus, which is influenced by factors such as impaired beta cell function and can be improved by physical activity.[57] (3) A condition where the body's cells do not respond properly to insulin, and is linked to the metabolic changes associated with HAART.[58] (4) This is often seen in combination with obesity and impaired beta cell function in individuals with Type 2 Diabetes Mellitus, as stated in the text.[59]
From: Journal of Medicinal Plants for Economic Development
(1) This is a condition where the body's cells do not respond properly to insulin, and the study of plants may reveal compounds that can help manage this condition.[60] (2) This was decreased with the administration of the saponin-rich extract of Lindackeria dentata at various dosages, as indicated in the study.[61] (3) Insulin resistance in individuals with type 2 diabetes reduces the ability of peripheral tissue cells to absorb and use glucose.[62]
From: International Journal of Environmental Research and Public Health (MDPI)
(1) Insulin resistance is discussed in relation to the possible molecular mechanism of action of N-acetylcysteine against insulin resistance.[63] (2) It is a condition in which cells do not respond effectively to a hormone, leading to elevated levels in the blood.[64] (3) Insulin resistance is estimated by TG / HDL-C, and may be mediated by visceral fat through the release of inflammatory adipokines, leading to intensified lipolysis and excess triglycerides entering the liver, causing abnormally high TG level.[65] (4) Insulin resistance refers to a condition where cells do not respond effectively to insulin, requiring higher levels of insulin to manage glucose, and MCS individuals may be more affected.[66] (5) The text mentions that smoking increases the risk of diabetes mellitus by affecting visceral abdominal fat accumulation and insulin resistance, which contributes to pancreatic b-cell dysfunction.[67]
From: Sustainability Journal (MDPI)
(1) The text suggests that including hypertension and insulin resistance, could result from a winter metabolism which increases thermogenic capacity.[68] (2) Insulin resistance is discussed in relation to central obesity, high diabetes prevalence, and cardiovascular risk, especially among South Asians.[69] (3) Type 2 diabetes is associated with developing insulin resistance, leading to long-term pathogenic conditions and vascular complications.[70]
From: International Journal of Pharmacology
(1) Insulin resistance is a condition implicated in numerous chronic metabolic and cardiovascular disorders, and its pathogenesis is influenced by the excessive accumulation of adipose tissue in the body.[71] (2) A key feature of Gestational Diabetes Mellitus where the body's cells do not respond effectively to insulin, hindering proper glucose uptake and utilization, and potentially linked to abnormal fat metabolism.[72] (3) Insulin resistance is a condition linked to resistin and obesity, where the body's cells do not respond effectively to insulin.[73] (4) A condition characterized by reduced sensitivity to insulin, which can be improved by treatments that promote adipogenesis.[74] (5) A condition where target cells fail to respond to normal circulating levels of insulin, often due to issues in the insulin-signaling pathway.[75]
From: South African Journal of Psychiatry
(1) This is a physiological condition that can contribute to diabetes, which was mentioned in relation to prevalence among certain racial groups.[76] (2) Metabolic consequences that should be the focus of attention include the effects on weight (gain) and the relationship, direct or indirect, with increased rates of insulin resistance, new-onset type 2 diabetes and dyslipidaemias.[77]