Significance of Innate immune response
Innate immune response, as described across various disciplines, is the body's immediate and non-specific first line of defense against pathogens. This rapid response involves physical barriers, immune cells, and signaling molecules, acting within hours of infection. It is crucial for containing infections and is activated by various triggers, including tissue damage and viral RNA. The response can be influenced by factors like vaccines, stress, and the specific pathogen involved, and it plays a significant role in conditions like COVID-19, tuberculosis, and liver injury.
Synonyms: Intrinsic immune response, Natural immune response, Natural immunity, Non-specific immune response, First line of defense, Congenital immunity
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Hindu concept of 'Innate immune response'
In Hinduism, the innate immune response acts as an immediate shield against pathogens. It's the body's initial defense mechanism, categorized as a crucial aspect of the immune system, offering swift protection from invading threats.
(1) The innate immune response is the body's first line of defense against pathogens, and it is one of the aspects of the immune system affected by the extracts.[1] (2) This type of immune response provides immediate shelter against an invading pathogen, and is one of the two ways the immune defence or response is categorized.[2]
The concept of Innate immune response in scientific sources
Innate immune response is the body's rapid, non-specific first line of defense against pathogens. It encompasses various mechanisms, including physical barriers and immune cells, that quickly respond to infections and tissue damage, often within minutes or hours. It is essential for initiating an immune response.
(1) This is a key part of the body's defense against tuberculosis, but the disease can be suppressed, allowing the infection to spread to the brain, as seen in the Euro-American strains.[3] (2) This is the body's first line of defense against infection, and liver injury may result from the induction of a dysregulated innate immune response.[4] (3) Mast cells influence tumour growth and metastasis by contributing to innate and adaptive immune responses in the tumour microenvironment, and these responses play a significant role.[5] (4) This is a controlled response that occurs during the early infection stage, and it manifests clinically as mild and often non-specific symptoms such as fever and cough.[6] (5) Immediate immune responses that occur after injection to eliminate viral components.[7]
(1) The immune response regulated by Gentianopsis paludosa through the down-regulation of TL1A/DR3, IL-1, and Caspase-8.[8] (2) The innate immune response refers to the body's natural defense mechanisms that are investigated in relation to conditions like sub-health and infections.[9] (3) This is the body's first line of defense against pathogens, involving rapid and non-specific reactions to foreign invaders.[10] (4) The body's first line of defense, a non-specific immunity that Dendrobium species were shown to improve in the studied mice.[11]
(1) The body's first line of defense against infection, and its severity is studied in relation to disease outcomes.[12]
(1) This is a feature of the polysaccharides present in the water extracts of S. frutescens that promote complement fixation, validating its traditional use.[13]
(1) The immune response to viral RNA that is triggered by RIG-1 inducers, which can activate apoptosis, and this response is a potential therapeutic avenue for eliminating latent human immunodeficiency virus.[14]